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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

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PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2015

PMID 25724093Rat

Protective effects of rosuvastatin in a rat model of lung contusion: Stimulation of the cyclooxygenase 2-prostaglandin E-2 pathway.

Other1 linked therapy

2015

PMID 25724274Mouse

Sponge-mediated lentivirus delivery to acute and chronic spinal cord injuries.

Spinal cord injury1 linked therapy

2015

PMID 25725354Rat

Pharmacologically induced hypothermia attenuates traumatic brain injury in neonatal rats.

TBI1 linked therapy

2015

PMID 25733010Rat

The effect of granulocyte-colony stimulating factor on rotator cuff healing after injury and repair.

Other1 linked therapy

2015

PMID 25738896Mouse

The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice.

Radiation1 linked therapy

2015

PMID 25738976Mouse

Anti-inflammatory effects of methanol extract of Canarium lyi C.D. Dai & Yakovlev in RAW 264.7 macrophages and a murine model of lipopolysaccharide-induced lung injury.

Endotoxin/LPS1 linked therapy

2015

PMID 25739763Rat

A synthetic fibrin cross-linking polymer for modulating clot properties and inducing hemostasis.

Haemorrhage/shock1 linked therapy

2015

PMID 25747047Mouse

Estrogen modulates 7/4 antigen distribution within eccentrically contracted injured skeletal muscle.

Other1 linked therapy

2015

PMID 25747661Mouse

The chemical inhibitors of cellular death, PJ34 and Necrostatin-1, down-regulate IL-33 expression in liver.

Chemical/toxin1 linked therapy

2015

PMID 25748849Mixed

Electrospun polyurethane-dextran nanofiber mats loaded with Estradiol for post-menopausal wound dressing.

Wound1 linked therapy

2015

PMID 25752620Mouse

Cyanidin-3-O-Glucoside Ameliorates Lipopolysaccharide-Induced Injury Both In Vivo and In Vitro Suppression of NF-kappaB and MAPK Pathways.

Endotoxin/LPS1 linked therapy

2015

PMID 25754765Rat

Protective effects of edaravone combined puerarin on inhalation lung injury induced by black gunpowder smog.

Chemical/toxin1 linked therapy

2015

PMID 25757124Rat

The effect of cyclosporine A in hemorrhagic shock model of rats.

Haemorrhage/shock1 linked therapy

2015

PMID 25768249Rat

PREVENTION OF RADIATION-INDUCED RETINOPATHY WITH AMIFOSTINE IN WISTAR ALBINO RATS.

Radiation1 linked therapy

2015

PMID 25768373Rat

Angiotensin-converting enzyme inhibition attenuates lipopolysaccharide-induced lung injury by regulating the balance between angiotensin-converting enzyme and angiotensin-converting enzyme 2 and inhibiting mitogen-activated protein kinase activation.

Endotoxin/LPS1 linked therapy

2015

PMID 25770829Rat

A combination of keratan sulfate digestion and rehabilitation promotes anatomical plasticity after rat spinal cord injury.

Spinal cord injury1 linked therapy

2015

PMID 25771151Rat

Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury.

TBI1 linked therapy

2015

PMID 25785578Rat

Effect of pregabalin in preventing secondary damage in traumatic brain injury: an experimental study.

TBI1 linked therapy

2015

PMID 25789543Rat

Serum Glial Fibrillary Acidic Protein Predicts Tissue Glial Fibrillary Acidic Protein Break-Down Products and Therapeutic Efficacy after Penetrating Ballistic-Like Brain Injury.

TBI1 linked therapy

2015

PMID 25791071Rat

Intravenous delivery of adipose-derived mesenchymal stromal cells attenuates acute radiation-induced lung injury in rats.

Radiation1 linked therapy

2015

PMID 25794265Rat

Dual Therapeutic Effects of C-10068, a Dextromethorphan Derivative, Against Post-Traumatic Nonconvulsive Seizures and Neuroinflammation in a Rat Model of Penetrating Ballistic-Like Brain Injury.

TBI1 linked therapy

2015

PMID 25797576Rat

The secretome of apoptotic human peripheral blood mononuclear cells attenuates secondary damage following spinal cord injury in rats.

Spinal cord injury1 linked therapy

2015

PMID 25798616Mouse

NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage.

Crush1 linked therapy

2015

PMID 25801039Rat

Effects of Wharton's jelly cells of the human umbilical cord on acute spinal cord injury in rats, and expression of interleukin-1beta and nerve growth factor in spinal cord tissues.

Spinal cord injury1 linked therapy

2015

PMID 25803613Rat

N-acetyl-L-leucine accelerates vestibular compensation after unilateral labyrinthectomy by action in the cerebellum and thalamus.

Chemical/toxin1 linked therapy

2015

PMID 25804610Mouse

Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans.

Radiation1 linked therapy

2015

PMID 25807318Mouse

Mitigation of the hematopoietic and gastrointestinal acute radiation syndrome by octadecenyl thiophosphate, a small molecule mimic of lysophosphatidic acid.

Radiation1 linked therapy

2015

PMID 25807405Rat

Can mesenchymal stem cells reverse chronic stress-induced impairment of lung healing following traumatic injury?

Other1 linked therapy

2015

PMID 25819102Rat

Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury.

TBI1 linked therapy

2015

PMID 25834818Rat

The effect of iloprost and N-acetylcysteine on skeletal muscle injury in an acute aortic ischemia-reperfusion model: an experimental study.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25839149Rat

The antidepressant fluoxetine protects the hippocampus from brain damage in experimental pneumococcal meningitis.

Other1 linked therapy

2015

PMID 25840803Mixed

TREM-1 Mediates Inflammatory Injury and Cardiac Remodeling Following Myocardial Infarction.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25845398Rat

Nanoparticle Estrogen in Rat Spinal Cord Injury Elicits Rapid Anti-Inflammatory Effects in Plasma, Cerebrospinal Fluid, and Tissue.

Spinal cord injury1 linked therapy

2015

PMID 25845487Mouse

Topical treatment with pterostilbene, a natural phytoalexin, effectively protects hairless mice against UVB radiation-induced skin damage and carcinogenesis.

Radiation1 linked therapy

2015

PMID 25852150Mouse

Radioprotective effects of Sipunculus nudus L. polysaccharide combined with WR-2721, rhIL-11 and rhG-CSF on radiation-injured mice.

Radiation1 linked therapy

2015

PMID 25854776Rat

Pirfenidone Attenuates Microglial Reactivity and Reduces Inducible Nitric Oxide Synthase mRNA Expression After Kainic Acid-Mediated Excitotoxicity in Pubescent Rat Hippocampus.

Chemical/toxin1 linked therapy

2015

PMID 25856291Rat

Xenon Treatment Protects against Remote Lung Injury after Kidney Transplantation in Rats.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25861814Rat

Functional Recovery of Carbon Nanotube/Nafion Nanocomposite in Rat Model of Spinal Cord Injury.

Spinal cord injury1 linked therapy

2015

PMID 25871290Rat

Astaxanthin attenuates early acute kidney injury following severe burns in rats by ameliorating oxidative stress and mitochondrial-related apoptosis.

Burn1 linked therapy

2015

PMID 25871534Rabbit

Substance P promotes wound healing in diabetes by modulating inflammation and macrophage phenotype.

Wound1 linked therapy

2015

PMID 25878401Rat

Hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced severe acute pancreatitis by inhibiting ROS and NF-κB pathway.

Chemical/toxin1 linked therapy

2015

PMID 25879397Mouse

Proneurotrophin Binding to P75 Neurotrophin Receptor (P75ntr) Is Essential for Brain Lesion Formation and Functional Impairment after Experimental Traumatic Brain Injury.

TBI1 linked therapy

2015

PMID 25880399Rat

Neuregulin-1 inhibits neuroinflammatory responses in a rat model of organophosphate-nerve agent-induced delayed neuronal injury.

Chemical/toxin1 linked therapy

2015

PMID 25886256Mouse

Attenuation of traumatic brain injury-induced cognitive impairment in mice by targeting increased cytokine levels with a small molecule experimental therapeutic.

TBI1 linked therapy

2015

PMID 25890041Rat

The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis.

Other1 linked therapy

2015

PMID 25891093Rat

Topical Aloe Vera (Aloe barbadensis Miller) Extract Does Not Accelerate the Oral Wound Healing in Rats.

Wound1 linked therapy

2015

PMID 25892998Mixed

Pharmacological Basis for Traditional Use of the Lippia thymoides.

Wound1 linked therapy

2015

PMID 25899606Rat

Ascorbic Acid Reduces the Adverse Effects of Delayed Administration of Tissue Plasminogen Activator in a Rat Stroke Model.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25900267Rat

Effect of photodynamic therapy on local muscle treatment in a rat muscle injury model: a controlled trial.

Crush1 linked therapy

2015

PMID 25901291Rat

Metformin attenuates myocardial remodeling and neutrophil recruitment after myocardial infarction in rat.

Other1 linked therapy

2,051–2,100 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.