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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

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PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2015

PMID 25164111Mouse

Gelsolin: role of a functional protein in mitigating radiation injury.

Radiation1 linked therapy

2015

PMID 25185931Mouse

Wound healing after thermal injury is improved by fat and adipose-derived stem cell isografts.

Burn1 linked therapy

2015

PMID 25243351Rat

Effects of oleuropein and pinoresinol on microvascular damage induced by hypoperfusion and reperfusion in rat pial circulation.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25270658Rat

Erythropoietin reduces acute lung injury and multiple organ failure/dysfunction associated to a scald-burn inflammatory injury in the rat.

Burn1 linked therapy

2015

PMID 25349036Rat

rhPDGF-BB promotes early healing in a rat rotator cuff repair model.

Other1 linked therapy

2015

PMID 25353067Mouse

Guanylyl cyclase activation reverses resistive breathing-induced lung injury and inflammation.

Other1 linked therapy

2015

PMID 25366938Mouse

Fluoxetine prevents oligodendrocyte cell death by inhibiting microglia activation after spinal cord injury.

Spinal cord injury1 linked therapy

2015

PMID 25424914Rat

Carvedilol promotes neurological function, reduces bone loss and attenuates cell damage after acute spinal cord injury in rats.

Spinal cord injury1 linked therapy

2015

PMID 25425209Mouse

Delta(9) Tetrahydrocannabinol attenuates Staphylococcal enterotoxin B-induced inflammatory lung injury and prevents mortality in mice by modulation of miR-17-92 cluster and induction of T-regulatory cells.

Other1 linked therapy

2015

PMID 25428204Rat

Inflammatory cytokines content in Achilles tendinopathy after phonophoresis treatment combined with gold nanoparticles and diclophenac diethylammonium in rats.

Other1 linked therapy

2015

PMID 25433073Mouse

Protection of intestinal injury during heat stroke in mice by interleukin-6 pretreatment.

Other1 linked therapy

2015

PMID 25445489Mouse

HINT1 protein: a new therapeutic target to enhance opioid antinociception and block mechanical allodynia.

Other1 linked therapy

2015

PMID 25484198Rat

PTH(1-34) Treatment Increases Bisphosphonate Turnover in Fracture Repair in Rats.

Fracture1 linked therapy

2015

PMID 25490571Rat

The effect of coenzyme Q10 on the regeneration of crushed facial nerve.

Crush1 linked therapy

2015

PMID 25539203Rat

A pharmacologic approach to vagal nerve stimulation prevents mesenteric lymph toxicity after hemorrhagic shock.

Haemorrhage/shock1 linked therapy

2015

PMID 25563839Mouse

Adventitial CXCL1/G-CSF expression in response to acute aortic dissection triggers local neutrophil recruitment and activation leading to aortic rupture.

Other1 linked therapy

2015

PMID 25565639Rat

The hydrocortisone protection of glycocalyx on the intestinal capillary endothelium during severe acute pancreatitis.

Chemical/toxin1 linked therapy

2015

PMID 25596429Mouse

Role of p53-fibrinolytic system cross-talk in the regulation of quartz-induced lung injury.

Chemical/toxin1 linked therapy

2015

PMID 25601009Rat

Protective effect of rhGLP-1 (7-36) on brain ischemia/reperfusion damage in diabetic rats.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25601293Mouse

Liver-specific Fas silencing prevents galactosamine/lipopolysaccharide-induced liver injury.

Endotoxin/LPS1 linked therapy

2015

PMID 25601496Mouse

Androctonus australis hector venom contributes to the interaction between neuropeptides and mast cells in pulmonary hyperresponsiveness.

Chemical/toxin1 linked therapy

2015

PMID 25616904Rat

Ebselen Attenuates Lung Injury in Experimental Model of Carrageenan-Induced Pleurisy in Rats.

Chemical/toxin1 linked therapy

2015

PMID 25618561Mouse

Hematopoietic recovery of acute radiation syndrome by human superoxide dismutase-expressing umbilical cord mesenchymal stromal cells.

Radiation1 linked therapy

2015

PMID 25619933Mouse

Combined mitigation of the gastrointestinal and hematopoietic acute radiation syndromes by an LPA2 receptor-specific nonlipid agonist.

Radiation1 linked therapy

2015

PMID 25625433Rat

Optimization of an injectable tendon hydrogel: the effects of platelet-rich plasma and adipose-derived stem cells on tendon healing in vivo.

Wound1 linked therapy

2015

PMID 25630025Rat

Dorsal root ganglion myeloid zinc finger protein 1 contributes to neuropathic pain after peripheral nerve trauma.

Crush1 linked therapy

2015

PMID 25635918Rat

Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors.

Spinal cord injury1 linked therapy

2015

PMID 25647147Rat

Tacrolimus prevents laryngotracheal stenosis in an acute-injury rat model.

Wound1 linked therapy

2015

PMID 25647402Mouse

Enhanced Resolution of Hyperoxic Acute Lung Injury as a result of Aspirin Triggered Resolvin D1 Treatment.

Other1 linked therapy

2015

PMID 25649295Rat

Response of inflamed pulps of rat molars after capping with pulp-capping material containing fluocinolone acetonide.

Other1 linked therapy

2015

PMID 25662912Rat

Optimization of multifunctional chitosan-siRNA nanoparticles for oral delivery applications, targeting TNF-alpha silencing in rats.

Chemical/toxin1 linked therapy

2015

PMID 25664481Rat

Delayed Intervention with Intermittent Hypoxia and Task Training Improves Forelimb Function in a Rat Model of Cervical Spinal Injury.

Spinal cord injury1 linked therapy

2015

PMID 25665753Rat

The effect of estrogen-related receptor alpha on the regulation of angiogenesis after spinal cord injury.

Spinal cord injury1 linked therapy

2015

PMID 25668593Mouse

Protective actions of PJ34, a poly(ADP-ribose)polymerase inhibitor, on the blood-brain barrier after traumatic brain injury in mice.

TBI1 linked therapy

2015

PMID 25672431Rat

Evaluation of the effects of ischemic preconditioning on the hematological parameters of rats subjected to intestinal ischemia and reperfusion.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25673840Rat

Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity.

Spinal cord injury1 linked therapy

2015

PMID 25676919Rat

Impact of beta-adrenoceptor blockade on systemic inflammation and coagulation disturbances in rats with acute traumatic coagulopathy.

Haemorrhage/shock1 linked therapy

2015

PMID 25684751Mouse

NAMPT inhibitor and metabolite protect mouse brain from cryoinjury through distinct mechanisms.

TBI1 linked therapy

2015

PMID 25686746Mouse

Sodium Butyrate Reduces Organ Injuries in Mice with Severe Acute Pancreatitis Through Inhibiting HMGB1 Expression.

Chemical/toxin1 linked therapy

2015

PMID 25686821Mouse

SKI2162, an inhibitor of the TGF-beta type I receptor (ALK5), inhibits radiation-induced fibrosis in mice.

Radiation1 linked therapy

2015

PMID 25687551Rat

Daily acute intermittent hypoxia elicits functional recovery of diaphragm and inspiratory intercostal muscle activity after acute cervical spinal injury.

Spinal cord injury1 linked therapy

2015

PMID 25690469Rat

Normobaric oxygen worsens outcome after a moderate traumatic brain injury.

TBI1 linked therapy

2015

PMID 25698749Mouse

Overexpression of Sox11 promotes corticospinal tract regeneration after spinal injury while interfering with functional recovery.

Spinal cord injury1 linked therapy

2015

PMID 25699264Rat

Comparison and efficacy of LigaSure and rubber band ligature in closing the inflamed cecal stump in a rat model of acute appendicitis.

Other1 linked therapy

2015

PMID 25701712Rat

Early applied electric field stimulation attenuates secondary apoptotic responses and exerts neuroprotective effects in acute spinal cord injury of rats.

Spinal cord injury1 linked therapy

2015

PMID 25704035Rat

Protective effects of caffeic acid phenethyl ester against acute radiation-induced hepatic injury in rats.

Radiation1 linked therapy

2015

PMID 25705671Rat

Salvianolic acids attenuate rat hippocampal injury after acute CO poisoning by improving blood flow properties.

Chemical/toxin1 linked therapy

2015

PMID 25705683Rat

Thaliporphine derivative improves acute lung injury after traumatic brain injury.

TBI1 linked therapy

2015

PMID 25705963Rat

Effects of Therapeutic Hypothermia on Apoptosis and Autophagy After Spinal Cord Injury in Rats.

Spinal cord injury1 linked therapy

2015

PMID 25710428Rat

Smoke inhalation injury repaired by a bone marrow-derived mesenchymal stem cell paracrine mechanism: Angiogenesis involving the Notch signaling pathway.

Chemical/toxin1 linked therapy

2,001–2,050 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.