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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2015

PMID 25904269Rat

The effects of caffeic acid phenethyl ester on inflammatory cytokines after acute spinal cord injury.

Spinal cord injury1 linked therapy

2015

PMID 25904764Mixed

Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25904802Mouse

The Complement Receptor C5aR Controls Acute Inflammation and Astrogliosis following Spinal Cord Injury.

Spinal cord injury1 linked therapy

2015

PMID 25909419Rat

Recombinant human brain natriuretic peptide ameliorates trauma-induced acute lung injury via inhibiting JAK/STAT signaling pathway in rats.

Other1 linked therapy

2015

PMID 25909427Mouse

SIRT1 mediates a primed response to immune challenge after traumatic lung injury.

Other1 linked therapy

2015

PMID 25909480Rat

Tissue responses to postoperative laser therapy in diabetic rats submitted to excisional wounds.

Wound1 linked therapy

2015

PMID 25909874Rat

Subdural infusion of dexamethasone inhibits leukomyelitis after acute spinal cord injury in a rat model.

Spinal cord injury1 linked therapy

2015

PMID 25911389Rat

Local Application of Gelatin Hydrogel Sheets Impregnated With Platelet-Derived Growth Factor BB Promotes Tendon-to-Bone Healing After Rotator Cuff Repair in Rats.

Other1 linked therapy

2015

PMID 25912803Rat

The monoacylglycerol lipase inhibitor JZL184 decreases inflammatory response in skeletal muscle contusion in rats.

Crush1 linked therapy

2015

PMID 25914996Rat

Delayed Imatinib Treatment for Acute Spinal Cord Injury: Functional Recovery and Serum Biomarkers.

Spinal cord injury1 linked therapy

2015

PMID 25916278Rat

Anti-edema effect of melatonin on spinal cord injury in rats.

Spinal cord injury1 linked therapy

2015

PMID 25925413Rat

Mallotus philippinensis Muell. Arg fruit glandular hairs extract promotes wound healing on different wound model in rats.

Wound1 linked therapy

2015

PMID 25926450Rat

Schwann cells generated from neonatal skin-derived precursors or neonatal peripheral nerve improve functional recovery after acute transplantation into the partially injured cervical spinal cord of the rat.

Spinal cord injury1 linked therapy

2015

PMID 25933588Mouse

Red blood cell washing, nitrite therapy, and antiheme therapies prevent stored red blood cell toxicity after trauma-hemorrhage.

Haemorrhage/shock1 linked therapy

2015

PMID 25934321Mouse

Enhancing repair of full-thickness excisional wounds in a murine model: Impact of tissue-engineered biological dressings featuring human differentiated adipocytes.

Wound1 linked therapy

2015

PMID 25936601Mixed

Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury.

Spinal cord injury1 linked therapy

2015

PMID 25938032Rat

Therapeutic effects of topical netrin-4 in a corneal acute inflammatory model.

Burn1 linked therapy

2015

PMID 25938566Mixed

The Reg3alpha (HIP/PAP) Lectin Suppresses Extracellular Oxidative Stress in a Murine Model of Acute Liver Failure.

Chemical/toxin1 linked therapy

2015

PMID 25943283Rat

Neuroprotective effects of MK-801 against traumatic brain injury in immature rats.

TBI1 linked therapy

2015

PMID 25947337Mouse

The Secretome of Hydrogel-Coembedded Endothelial Progenitor Cells and Mesenchymal Stem Cells Instructs Macrophage Polarization in Endotoxemia.

Endotoxin/LPS1 linked therapy

2015

PMID 25950489Mouse

Divergent effects of RIP1 or RIP3 blockade in murine models of acute liver injury.

Chemical/toxin1 linked therapy

2015

PMID 25950535Rat

Enhancement of acute tendon repair using chitosan matrix.

Other1 linked therapy

2015

PMID 25961471Rat

Delayed Methylene Blue Improves Lesion Volume, Multi-Parametric Quantitative Magnetic Resonance Imaging Measurements, and Behavioral Outcome after Traumatic Brain Injury.

TBI1 linked therapy

2015

PMID 25966123Rat

Neuroprotective effect of ketamine on acute spinal cord injury in rats.

Spinal cord injury1 linked therapy

2015

PMID 25966182Rat

Effects of autologous SCF- and G-CSF-mobilized bone marrow stem cells on hypoxia-inducible factor-1 in rats with ischemia-reperfusion renal injury.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25968480Rat

Mitochondrial Division Inhibitor 1 Ameliorates Mitochondrial Injury, Apoptosis, and Motor Dysfunction After Acute Spinal Cord Injury in Rats.

Spinal cord injury1 linked therapy

2015

PMID 25973006Rat

BQ-869, a novel NMDA receptor antagonist, protects against excitotoxicity and attenuates cerebral ischemic injury in stroke.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25973008Rat

Resveratrol attenuates spinal cord injury-induced inflammatory damage in rat lungs.

Spinal cord injury1 linked therapy

2015

PMID 25973651Rat

Stimulation of cutaneous wound healing by an FPR2-specific peptide agonist WKYMVm.

Wound1 linked therapy

2015

PMID 25974843Rat

Sclerostin antibody preserves the morphology and structure of osteocytes and blocks the severe skeletal deterioration after motor-complete spinal cord injury in rats.

Spinal cord injury1 linked therapy

2015

PMID 25975053Mixed

Effect of Yajieshaba, a preparation of Dai indigenous medicine, on enhanced liver detoxification.

Chemical/toxin1 linked therapy

2015

PMID 25976749Rat

Sarin-induced brain damage in rats is attenuated by delayed administration of midazolam.

Chemical/toxin1 linked therapy

2015

PMID 25977259Rat

The effects of pentoxifylline and caffeic acid phenethyl ester in the treatment of d-galactosamine-induced acute hepatitis in rats.

Chemical/toxin1 linked therapy

2015

PMID 25979115Rat

Acute theophylline exposure modulates breathing activity through a cervical contusion.

Spinal cord injury1 linked therapy

2015

PMID 25982374Rat

Hyperbaric oxygen effects on neuronal apoptosis associations in a traumatic brain injury rat model.

TBI1 linked therapy

2015

PMID 25982564Rat

Traumatic brain injury causes frontotemporal dementia and TDP-43 proteolysis.

TBI1 linked therapy

2015

PMID 25989500Rat

Stimulation of Dopamine D3 Receptor Attenuates Renal Ischemia-Reperfusion Injury via Increased Linkage With Galpha12.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25992481Rat

SIRT1 protects rat lung tissue against severe burn-induced remote ALI by attenuating the apoptosis of PMVECs via p38 MAPK signaling.

Burn1 linked therapy

2015

PMID 25994490Rat

The role of PPAR activation during the systemic response to brain injury.

Ischaemia-reperfusion1 linked therapy

2015

PMID 25994811Mouse

Attenuation of radiation-induced gastrointestinal damage by epidermal growth factor and bone marrow transplantation in mice.

Radiation1 linked therapy

2015

PMID 25999385Mouse

Evidence That Ly6C(hi) Monocytes are Protective in Acute Ischemic Stroke by Promoting M2 Macrophage Polarization.

Ischaemia-reperfusion1 linked therapy

2015

PMID 26002267Mouse

Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock.

Haemorrhage/shock1 linked therapy

2015

PMID 26004679Mouse

Acute administration of ucf-101 ameliorates the locomotor impairments induced by a traumatic spinal cord injury.

Spinal cord injury1 linked therapy

2015

PMID 26004757Rat

Dextromethorphan provides neuroprotection via anti-inflammatory and anti-excitotoxicity effects in the cortex following traumatic brain injury.

TBI1 linked therapy

2015

PMID 26021285Rat

EGb761 Ameliorates Neuropathic Pain by Scavenging Reactive Oxygen Species.

Other1 linked therapy

2015

PMID 26023063Rat

Valproic Acid Arrests Proliferation but Promotes Neuronal Differentiation of Adult Spinal NSPCs from SCI Rats.

Spinal cord injury1 linked therapy

2015

PMID 26025319Mouse

m-Trifluoromethyl-diphenyl diselenide, a multi-target selenium compound, prevented mechanical allodynia and depressive-like behavior in a mouse comorbid pain and depression model.

Other1 linked therapy

2015

PMID 26029925Mouse

Coniferyl aldehyde attenuates radiation enteropathy by inhibiting cell death and promoting endothelial cell function.

Radiation1 linked therapy

2015

PMID 26039663Rat

Tramadol alleviates myocardial injury induced by acute hindlimb ischemia reperfusion in rats.

Ischaemia-reperfusion1 linked therapy

2015

PMID 26039701Rat

Contusive spinal cord injury up regulates mu-opioid receptor (mor) gene expression in the brain and down regulates its expression in the spinal cord: possible implications in spinal cord injury research.

Spinal cord injury1 linked therapy

2,101–2,150 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.