Four decades of research.
A clearer way forward.
Trace the journey from preclinical promise to human evidence. Explore therapies, clinical trials and regulatory outcomes across 40 years of acute-injury research.
Big questions.
In one place.
Find the evidence that matters.
For researchers asking what comes next.
For teams deciding where to invest their effort.
Has this approach reached humans?
Follow a therapy from rodent studies to registered clinical trials and reported regulatory status.
Explore therapiesWhat happened to the mechanism?
Look beyond individual compounds. Explore mechanism classes, clinical setbacks and gaps in the evidence.
Explore mechanismsHow strong is the evidence?
Return to the underlying publications, inspect provenance and understand the limits of each finding.
Explore studiesUseful evidence starts
with honest limitations.
The atlas connects a systematic review with an extended, machine-assisted evidence index. It records reported outcomes; it does not establish that an animal study caused a clinical approval.
Coverage and definitions are visible throughout. The research window is 1980–2020; clinical and regulatory information reflects the August 2026 dataset.
Read the methods and limitations