Skip to content

RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

Loading the evidence…

Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

Year Sort by Reset

Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2018

PMID 29713644Rat

The Therapeutic Effects after Transplantation of Whole-Layer Olfactory Mucosa in Rats with Optic Nerve Injury.

Crush1 linked therapy

2018

PMID 29713995Rat

Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats.

Chemical/toxin1 linked therapy

2018

PMID 29723988Mouse

Dietary alpha-Mangostin Provides Protective Effects against Acetaminophen-Induced Hepatotoxicity in Mice via Akt/mTOR-Mediated Inhibition of Autophagy and Apoptosis.

Chemical/toxin1 linked therapy

2018

PMID 29727731Mouse

Effects of long-term rapamycin treatment on glial scar formation after cryogenic traumatic brain injury in mice.

TBI1 linked therapy

2018

PMID 29728112Mouse

Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion-induced acute kidney injury.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29732888Mouse

Nanoencapsulation of Cyanidin-3-O-glucoside Enhances Protection Against UVB-Induced Epidermal Damage through Regulation of p53-Mediated Apoptosis in Mice.

Radiation1 linked therapy

2018

PMID 29733976Rat

Ebselen protects mitochondrial function and oxidative stress while inhibiting the mitochondrial apoptosis pathway after acute spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29740965Rat

Comparative Evaluation of Chitosan Nerve Guides with Regular or Increased Bendability for Acute and Delayed Peripheral Nerve Repair: A Comprehensive Comparison with Autologous Nerve Grafts and Muscle-in-Vein Grafts.

Other1 linked therapy

2018

PMID 29742498Mouse

FG-4592 Accelerates Cutaneous Wound Healing by Epidermal Stem Cell Activation via HIF-1alpha Stabilization.

Wound1 linked therapy

2018

PMID 29743312Mouse

Survival of Mice with Gastrointestinal Acute Radiation Syndrome through Control of Bacterial Translocation.

Radiation1 linked therapy

2018

PMID 29749987Rat

The Preventive Role of Pioglitazone in Glycerol-Induced Acute Kidney Injury in Rats during Two Different Treatment Periods.

Chemical/toxin1 linked therapy

2018

PMID 29750991Rat

Celastrol attenuates incision-induced inflammation and pain associated with inhibition of the NF-kappaB signalling pathway via SARM.

Wound1 linked therapy

2018

PMID 29752337Mouse

OA-GL21, a novel bioactive peptide from, accelerated the healing of skin wounds.

Wound1 linked therapy

2018

PMID 29759062Mouse

Inhibition of 2-AG hydrolysis differentially regulates blood brain barrier permeability after injury.

Endotoxin/LPS1 linked therapy

2018

PMID 29760082Mouse

A cytokine network involving IL-36gamma, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage.

Other1 linked therapy

2018

PMID 29768539Rat

Evaluation of prophylactic and therapeutic effects of sildenafil on acute radiation proctitis in rats.

Radiation1 linked therapy

2018

PMID 29775479Rat

Acute intermittent hypoxia and rehabilitative training following cervical spinal injury alters neuronal hypoxia- and plasticity-associated protein expression.

Spinal cord injury1 linked therapy

2018

PMID 29776437Rat

Coenzyme Q10 combined with trimetazidine in the prevention of contrast-induced nephropathy in patients with coronary heart disease complicated with renal dysfunction undergoing elective cardiac catheterization: a randomized control study and in vivo study.

Chemical/toxin1 linked therapy

2018

PMID 29786827Rat

The protective effect of Montelukast against skeletal muscle ischemia reperfusion injury: An experimental rat model.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29787432Mouse

PEGylated IL-11 (BBT-059): A Novel Radiation Countermeasure for Hematopoietic Acute Radiation Syndrome.

Radiation1 linked therapy

2018

PMID 29787539Mouse

A concomitant bone fracture delays cognitive recovery from traumatic brain injury.

TBI1 linked therapy

2018

PMID 29787581Rat

Autologous and not allogeneic adipose-derived stem cells improve acute burn wound healing.

Burn1 linked therapy

2018

PMID 29796991Rat

Stem Cells from Human Exfoliated Deciduous Teeth Modulate Early Astrocyte Response after Spinal Cord Contusion.

Spinal cord injury1 linked therapy

2018

PMID 29802017Mouse

Topical Lyophilized Targeted Lipid Nanoparticles in the Restoration of Skin Barrier Function following Burn Wound.

Burn1 linked therapy

2018

PMID 29806211Rat

Electrospun Heparin-Loaded Core-Shell Nanofiber Sutures for Achilles Tendon Regeneration In Vivo.

Other1 linked therapy

2018

PMID 29806709Mouse

Relaxin-2 therapy reverses radiation-induced fibrosis and restores bladder function in mice.

Radiation1 linked therapy

2018

PMID 29807362Rat

Exosomes from MiR-30d-5p-ADSCs Reverse Acute Ischemic Stroke-Induced, Autophagy-Mediated Brain Injury by Promoting M2 Microglial/Macrophage Polarization.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29843672Rat

Effects of controlled abnormal joint movement on the molecular biological response in intra-articular tissues during the acute phase of anterior cruciate ligament injury in a rat model.

Other1 linked therapy

2018

PMID 29845137Rat

Cetuximab and Taxol co-modified collagen scaffolds show combination effects for the repair of acute spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29845594Mouse

Tissue-engineered biological dressing accelerates skin wound healing in mice via formation of provisional connective tissue.

Wound1 linked therapy

2018

PMID 29851904Rat

High-dose Factor XIII administration induces effective hemostasis for trauma-associated coagulopathy (TAC) both in vitro and in rat hemorrhagic shock in vivo models.

Haemorrhage/shock1 linked therapy

2018

PMID 29852289Mouse

Sex differences in the effects of PARP inhibition on microglial phenotypes following neonatal stroke.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29857242Rat

Protective role of beta-carotene against oxidative stress and neuroinflammation in a rat model of spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29860396Rat

Eliciting inflammation enables successful rehabilitative training in chronic spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29864436Mouse

Caffeic acid phenethyl ester promotes wound healing of mice pressure ulcers affecting NF-kappaB, NOS2 and NRF2 expression.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29867467Rat

Metabolomic Assessment of Acute Cholestatic Injuries Induced by Thioacetamide and by Bile Duct Ligation, and the Protective Effects of Huang-Lian-Jie-Du-Decoction.

Chemical/toxin1 linked therapy

2018

PMID 29867926Rat

Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage.

Haemorrhage/shock1 linked therapy

2018

PMID 29869055Mouse

Pyruvate Kinase M2 Increases Angiogenesis, Neurogenesis, and Functional Recovery Mediated by Upregulation of STAT3 and Focal Adhesion Kinase Activities After Ischemic Stroke in Adult Mice.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29870221Mouse

Modulation of Angiogenic Activity by Light-Activatable miRNA-Loaded Nanocarriers.

Wound1 linked therapy

2018

PMID 29883817Rat

Mesencephalic Astrocyte-Derived Neurotrophic Factor Prevents Traumatic Brain Injury in Rats by Inhibiting Inflammatory Activation and Protecting the Blood-Brain Barrier.

TBI1 linked therapy

2018

PMID 29886252Mouse

The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury.

TBI1 linked therapy

2018

PMID 29889084Mouse

Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29889090Mouse

Assessment of systemic administration of PEGylated IGF-1 in a mouse model of traumatic brain injury.

TBI1 linked therapy

2018

PMID 29890255Mixed

A novel Ca current blocker promotes angiogenesis and cardiac healing after experimental myocardial infarction in mice.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29901416Rat

Intravenous Infusion of Mesenchymal Stem Cells Alters Motor Cortex Gene Expression in a Rat Model of Acute Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29902384Rat

Abrupt Deflation after Sustained Inflation Causes Lung Injury.

Other1 linked therapy

2018

PMID 29902864Mouse

Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress.

Chemical/toxin1 linked therapy

2018

PMID 29906391Rat

Enhanced Rotator-Cuff Repair Using Platelet-Rich Plasma Adsorbed on Branched Poly(ester urea)s.

Other1 linked therapy

2018

PMID 29907135Rat

Doxorubicin-induced cardiotoxicity is suppressed by estrous-staged treatment and exogenous 17beta-estradiol in female tumor-bearing spontaneously hypertensive rats.

Chemical/toxin1 linked therapy

2018

PMID 29907375Rat

FNDC5 expression in Purkinje neurons of adult male rats with acute spinal cord injury following treatment with methylprednisolone.

Spinal cord injury1 linked therapy

1,001–1,050 of 4,095

PreviousPage 21 of 82Next

The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.