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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

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PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2018

PMID 29912852Rat

Emodin Attenuates Autophagy Response to Protect the Pancreas From Acute Pancreatitis Failure.

Chemical/toxin1 linked therapy

2018

PMID 29914983Rat

Inhibition of the cyclophilin A-CD147 interaction attenuates right ventricular injury and dysfunction after acute pulmonary embolism in rats.

Other1 linked therapy

2018

PMID 29920357Mixed

In vivo wound-healing activity of Euphorbia characias subsp. wulfenii: Isolation and quantification of quercetin glycosides as bioactive compounds.

Wound1 linked therapy

2018

PMID 29921384Rat

VEGF-A expression in soft tissues repaired by shockwave therapy: differences between modalities.

Fracture1 linked therapy

2018

PMID 29922560Mixed

The Utility of Silk-elastin Hydrogel as a New Material for Wound Healing.

Wound1 linked therapy

2018

PMID 29923422Rat

Anti-inflammatory and anti-fibrotic treatment in a rodent model of acute lung injury induced by sulfur dioxide.

Chemical/toxin1 linked therapy

2018

PMID 29925650Mouse

Optogenetic Inhibition of CGRPalpha Sensory Neurons Reveals Their Distinct Roles in Neuropathic and Incisional Pain.

Other1 linked therapy

2018

PMID 29925937Mouse

Attenuation of ventilation-induced diaphragm dysfunction through toll-like receptor 4 and nuclear factor-kappaB in a murine endotoxemia model.

Endotoxin/LPS1 linked therapy

2018

PMID 29927623Mouse

Modulating Glucose Metabolism and Lactate Synthesis in Injured Mouse Tendons: Treatment With Dichloroacetate, a Lactate Synthesis Inhibitor, Improves Tendon Healing.

Other1 linked therapy

2018

PMID 29927790Rat

Microglial P2X4R-evoked pain hypersensitivity is sexually dimorphic in rats.

Other1 linked therapy

2018

PMID 29928110Rat

Theaflavin alleviates inflammatory response and brain injury induced by cerebral hemorrhage via inhibiting the nuclear transcription factor kappa beta-related pathway in rats.

Haemorrhage/shock1 linked therapy

2018

PMID 29929403Rat

Biomechanical properties of the repaired and non-repaired rat supraspinatus tendon in the acute postoperative period.

Other1 linked therapy

2018

PMID 29929404Rat

Short time insulin treatment post burn improves elastic-collagen rearrangement and reepithelization.

Burn1 linked therapy

2018

PMID 29931461Rat

Sclerostin Antibody Reverses the Severe Sublesional Bone Loss in Rats After Chronic Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29934690Mouse

Knockdown of MicroRNA-21 Promotes Neurological Recovery After Acute Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29935950Mouse

Youthful systemic milieu alleviates renal ischemia-reperfusion injury in elderly mice.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29936362Mouse

Anti-hyperalgesic effects of two sphingosine derivatives in different acute and chronic models of hyperalgesia in mice.

Chemical/toxin1 linked therapy

2018

PMID 29936461Mouse

Accelerated Wound Healing on the Skin Using a Film Dressing with beta-Glucan Paramylon.

Wound1 linked therapy

2018

PMID 29941674Mouse

von Willebrand factor enhances microvesicle-induced vascular leakage and coagulopathy in mice with traumatic brain injury.

TBI1 linked therapy

2018

PMID 29952818Rat

Incisional Nociceptive Input Impairs Attention-related Behavior and Is Associated with Reduced Neuronal Activity in the Prefrontal Cortex in Rats.

Wound1 linked therapy

2018

PMID 29957300Mouse

Naringin protects acrolein-induced pulmonary injuries through modulating apoptotic signaling and inflammation signaling pathways in mice.

Chemical/toxin1 linked therapy

2018

PMID 29958015Mouse

Inhaled TRIM72 Protein Protects Ventilation Injury to the Lung through Injury-guided Cell Repair.

Other1 linked therapy

2018

PMID 29958959Mouse

Lycium europaeum Linn as a source of polysaccharide with in vitro antioxidant activities and in vivo anti-inflammatory and hepato-nephroprotective potentials.

Chemical/toxin1 linked therapy

2018

PMID 29959050Mouse

Interleukin 15 blockade protects the brain from cerebral ischemia-reperfusion injury.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29962076Mouse

Pifithrin-mu modulates microglial activation and promotes histological recovery following spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29969326Rat

Beta-Hydroxy-Beta-Methyl-Butyrate, L-glutamine, and L-arginine Supplementation Improves Radiation-Induce Acute Intestinal Toxicity.

Radiation1 linked therapy

2018

PMID 29969638Mouse

Protective effect of polysaccharide from Agaricus bisporus in Tibet area of China against tetrachloride-induced acute liver injury in mice.

Chemical/toxin1 linked therapy

2018

PMID 29970894Rat

Therapeutic effect of dental pulp stem cell transplantation on a rat model of radioactivity-induced esophageal injury.

Radiation1 linked therapy

2018

PMID 29971752Rat

Enhanced cutaneous wound healing in rats following topical delivery of insulin-loaded nanoparticles embedded in poly(vinyl alcohol)-borate hydrogels.

Wound1 linked therapy

2018

PMID 29976507Mouse

Decorin-Modified Umbilical Cord Mesenchymal Stem Cells (MSCs) Attenuate Radiation-Induced Lung Injuries via Regulating Inflammation, Fibrotic Factors, and Immune Responses.

Radiation1 linked therapy

2018

PMID 29981795Mouse

Aldehyde dehydrogenase 2 activation ameliorates cyclophosphamide-induced acute cardiotoxicity via detoxification of toxic aldehydes and suppression of cardiac cell death.

Chemical/toxin1 linked therapy

2018

PMID 29983824Mixed

Novel Lipid Signaling Mediators for Mesenchymal Stem Cell Mobilization during Bone Repair.

Fracture1 linked therapy

2018

PMID 29985239Mixed

Quetiapine protects the blood-brain barrier in traumatic brain injury.

TBI1 linked therapy

2018

PMID 29992491Rat

PBMT and topical diclofenac as single and combined treatment on skeletal muscle injury in diabetic rats: effects on biochemical and functional aspects.

Crush1 linked therapy

2018

PMID 29995562Rat

Knockdown of lncRNA BDNF-AS suppresses neuronal cell apoptosis via downregulating miR-130b-5p target gene PRDM5 in acute spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29996558Mouse

Recombinant Leucine-Rich Repeat Flightless-Interacting Protein-1 Improves Healing of Acute Wounds through Its Effects on Proliferation Inflammation and Collagen Deposition.

Wound1 linked therapy

2018

PMID 29997055Mouse

The anti-inflammatory and anti-oxidative actions of eugenol improve lipopolysaccharide-induced lung injury.

Endotoxin/LPS1 linked therapy

2018

PMID 29997302Mouse

Repetitive ischemic injuries to the kidneys result in lymph node fibrosis and impaired healing.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30001721Mouse

The novel estrogenic receptor GPR30 alleviates ischemic injury by inhibiting TLR4-mediated microglial inflammation.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30003692Mouse

In vivo GDF3 administration abrogates aging related muscle regeneration delay following acute sterile injury.

Chemical/toxin1 linked therapy

2018

PMID 30011298Mouse

Bioluminescent murine models of bacterial sepsis and scald wound infections for antimicrobial efficacy testing.

Burn1 linked therapy

2018

PMID 30013022Mouse

Dexmedetomidine Protects Against Traumatic Brain Injury-Induced Acute Lung Injury in Mice.

TBI1 linked therapy

2018

PMID 30013616Rat

Effect of Da-Cheng-Qi decoction for treatment of acute kidney injury in rats with severe acute pancreatitis.

Chemical/toxin1 linked therapy

2018

PMID 30024093Rat

Photobiomodulation and different macrophages phenotypes during muscle tissue repair.

Crush1 linked therapy

2018

PMID 30025145Mouse

Tumor Necrosis Factor Inhibition in the Acute Management of Traumatic Optic Neuropathy.

Crush1 linked therapy

2018

PMID 30025561Mouse

MMP Inhibitor Ilomastat Improves Survival of Mice Exposed to gamma-Irradiation.

Radiation1 linked therapy

2018

PMID 30028919Rat

Protective effects of hyperbaric oxygen preconditioning against LPS-induced acute lung injury in rats.

Endotoxin/LPS1 linked therapy

2018

PMID 30030404Mouse

Neuropathic Pain Creates an Enduring Prefrontal Cortex Dysfunction Corrected by the Type II Diabetic Drug Metformin But Not by Gabapentin.

Other1 linked therapy

2018

PMID 30031156Mouse

Cypin: A novel target for traumatic brain injury.

TBI1 linked therapy

2018

PMID 30038493Rat

Dextran-based biodegradable nanoparticles: an alternative and convenient strategy for treatment of traumatic spinal cord injury.

Spinal cord injury1 linked therapy

1,051–1,100 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.