Skip to content

RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

Loading the evidence…

Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

Year Sort by Reset

Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2018

PMID 29538234Mouse

Intravenous administration of synthetic platelets (SynthoPlate) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis.

Haemorrhage/shock1 linked therapy

2018

PMID 29540209Rat

Celastrol treatment protects against acute ischemic stroke-induced brain injury by promoting an IL-33/ST2 axis-mediated microglia/macrophage M2 polarization.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29545181Mouse

Inhibition of insulin-like growth factor receptor-1 reduces necroptosis-related markers and attenuates LPS-induced lung injury in mice.

Endotoxin/LPS1 linked therapy

2018

PMID 29553981Mouse

Local Administration of Interleukin-1 Receptor Antagonist Improves Diabetic Wound Healing.

Wound1 linked therapy

2018

PMID 29554045Rat

Adenosine, lidocaine, and Mg2+ (ALM) resuscitation fluid protects against experimental traumatic brain injury.

TBI1 linked therapy

2018

PMID 29558718Rat

Panax quinquefolius saponin inhibits endoplasmic reticulum stress-mediated apoptosis and neurite injury and improves functional recovery in a rat spinal cord injury model.

Spinal cord injury1 linked therapy

2018

PMID 29558941Rat

Perturbing chondroitin sulfate proteoglycan signaling through LAR and PTPsigma receptors promotes a beneficial inflammatory response following spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29565500Rat

Expression of Nrf2-Keap1-ARE signal pathway in traumatic lung injury and functional study.

Crush1 linked therapy

2018

PMID 29566345Mouse

Wnt-Responsive Odontoblasts Secrete New Dentin after Superficial Tooth Injury.

Other1 linked therapy

2018

PMID 29567576Mouse

The human natural killer-1 (HNK-1) glycan mimetic ursolic acid promotes functional recovery after spinal cord injury in mouse.

Spinal cord injury1 linked therapy

2018

PMID 29568898Rat

Adiponectin protects against lung ischemia-reperfusion injury in rats with type 2 diabetes mellitus.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29572175Rat

Motor Cortex Stimulation Regenerative Effects in Peripheral Nerve Injury: An Experimental Rat Model.

Other1 linked therapy

2018

PMID 29572206Mouse

Roles of PAD4 and NETosis in Experimental Atherosclerosis and Arterial Injury: Implications for Superficial Erosion.

Other1 linked therapy

2018

PMID 29573620Mouse

Sesquiterpenoids from the root of Panax Ginseng protect CCl-induced acute liver injury by anti-inflammatory and anti-oxidative capabilities in mice.

Chemical/toxin1 linked therapy

2018

PMID 29579707Mouse

Arctigenin protects against liver injury from acute hepatitis by suppressing immune cells in mice.

Chemical/toxin1 linked therapy

2018

PMID 29582398Mouse

The Synthetic Steroid Tibolone Decreases Reactive Gliosis and Neuronal Death in the Cerebral Cortex of Female Mice After a Stab Wound Injury.

TBI1 linked therapy

2018

PMID 29584451Mouse

Epithelial Heparan Sulfate Contributes to Alveolar Barrier Function and Is Shed during Lung Injury.

Endotoxin/LPS1 linked therapy

2018

PMID 29595543Mouse

Protective Effect of Scopoletin Against Cerulein-Induced Acute Pancreatitis and Associated Lung Injury in Mice.

Chemical/toxin1 linked therapy

2018

PMID 29605028Rat

Pyruvate as a novel carrier of hydroxyethyl starch 130/0.4 may protect kidney in rats subjected to severe burns.

Burn1 linked therapy

2018

PMID 29614703Rat

Potential risk of clonally expanded amnion mesenchymal stem cell transplants in contused spinal cords.

Spinal cord injury1 linked therapy

2018

PMID 29615639Mouse

TRPM7 in CHBP-induced renoprotection upon ischemia reperfusion-related injury.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29615933Mouse

Dexamethasone Protects Against Tourniquet-Induced Acute Ischemia-Reperfusion Injury in Mouse Hindlimb.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29617695Mouse

Topical Treatment of Skin Injury Inflicted in Mice by X-Ray Irradiation.

Radiation1 linked therapy

2018

PMID 29618365Mouse

Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury.

TBI1 linked therapy

2018

PMID 29621597Mouse

Mesenchymal stem cells encapsulated into biomimetic hydrogel scaffold gradually release CCL2 chemokine in situ preserving cytoarchitecture and promoting functional recovery in spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29622561Rat

O-Linked beta-N-Acetylglucosamine Modification of A20 Enhances the Inhibition of NF-kappaB (Nuclear Factor-kappaB) Activation and Elicits Vascular Protection After Acute Endoluminal Arterial Injury.

Other1 linked therapy

2018

PMID 29627448Mouse

Maslinic acid protects against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice.

Endotoxin/LPS1 linked therapy

2018

PMID 29629491Mouse

Regulation of Autophagy Affects the Prognosis of Mice with Severe Acute Pancreatitis.

Chemical/toxin1 linked therapy

2018

PMID 29631142Mouse

Navy and black bean supplementation attenuates colitis-associated inflammation and colonic epithelial damage.

Chemical/toxin1 linked therapy

2018

PMID 29631367Rat

Long noncoding RNA MALAT1 contributes to inflammatory response of microglia following spinal cord injury via the modulation of a miR-199b/IKKbeta/NF-kappaB signaling pathway.

Spinal cord injury1 linked therapy

2018

PMID 29632660Mouse

Ghrelin therapy mitigates bone marrow injury and splenocytopenia by sustaining circulating G-CSF and KC increases after irradiation combined with wound.

Radiation1 linked therapy

2018

PMID 29635131Rat

Betaine treatment protects liver through regulating mitochondrial function and counteracting oxidative stress in acute and chronic animal models of hepatic injury.

Chemical/toxin1 linked therapy

2018

PMID 29635617Mixed

Surfactant Dysfunction in ARDS and Bronchiolitis is Repaired with Cyclodextrins.

Other1 linked therapy

2018

PMID 29642394Mouse

Neuroprotective Effects of Platonin, a Therapeutic Immunomodulating Medicine, on Traumatic Brain Injury in Mice after Controlled Cortical Impact.

TBI1 linked therapy

2018

PMID 29642434Rat

A Single Dose of Atorvastatin Applied Acutely after Spinal Cord Injury Suppresses Inflammation, Apoptosis, and Promotes Axon Outgrowth, Which Might Be Essential for Favorable Functional Outcome.

Spinal cord injury1 linked therapy

2018

PMID 29648974Mouse

Traumatic Brain Injury-Induced Acute Lung Injury: Evidence for Activation and Inhibition of a Neural-Respiratory-Inflammasome Axis.

TBI1 linked therapy

2018

PMID 29648982Rat

Effects of Mitochondrial Transplantation on Bioenergetics, Cellular Incorporation, and Functional Recovery after Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29648984Mouse

Facilitation of Locomotor Spinal Networks Activity by Buspirone after a Complete Spinal Cord Lesion in Mice.

Spinal cord injury1 linked therapy

2018

PMID 29649629Mouse

Qingchangligan formula alleviates acute liver injury by attenuating extracellular histone-associated inflammation.

Chemical/toxin1 linked therapy

2018

PMID 29650044Rat

Human amnion-derived mesenchymal stem cells alleviate lung injury induced by white smoke inhalation in rats.

Chemical/toxin1 linked therapy

2018

PMID 29672156Mouse

Ursodeoxycholic acid protects against intestinal barrier breakdown by promoting enterocyte migration via EGFR- and COX-2-dependent mechanisms.

Endotoxin/LPS1 linked therapy

2018

PMID 29677640Mouse

18β-Glycyrrhetinic acid mitigates radiation-induced skin damage via NADPH oxidase/ROS/p38MAPK and NF-κB pathways.

Radiation1 linked therapy

2018

PMID 29680681Mouse

HDAC inhibition helps post-MI healing by modulating macrophage polarization.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29680773Rat

Changes in the hippocampal and peripheral phospholipid profiles are associated with neurodegeneration hallmarks in a long-term global cerebral ischemia model: Attenuation by Linalool.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29681233Rat

Topical oral wound healing potential of anthocyanin complex: animal and clinical studies.

Wound1 linked therapy

2018

PMID 29684352Mouse

Nrf2 activation protects against intratracheal LPS induced mouse/murine acute respiratory distress syndrome by regulating macrophage polarization.

Endotoxin/LPS1 linked therapy

2018

PMID 29698747Rat

Neuroprotective effects of metformin on traumatic brain injury in rats associated with NF-κB and MAPK signaling pathway.

TBI1 linked therapy

2018

PMID 29702279Rat

Cordycepin alleviates lipopolysaccharide-induced acute lung injury via Nrf2/HO-1 pathway.

Endotoxin/LPS1 linked therapy

2018

PMID 29707971Rat

Human Multilineage-differentiating Stress-Enduring Cells Exert Pleiotropic Effects to Ameliorate Acute Lung Ischemia-Reperfusion Injury in a Rat Model.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29708866Mouse

The Characterization of Monoclonal Antibodies to Mouse TLT-1 Suggests That TLT-1 Plays a Role in Wound Healing.

Burn1 linked therapy

951–1,000 of 4,095

PreviousPage 20 of 82Next

The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.