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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2018

PMID 29374192Mouse

Novel mechanisms of Collagenase Santyl Ointment (CSO) in wound macrophage polarization and resolution of wound inflammation.

Wound1 linked therapy

2018

PMID 29377249Mouse

HMGB1-induced inflammatory response promotes bone healing in murine tooth extraction socket.

Wound1 linked therapy

2018

PMID 29380749Rat

Injectable hydrogels of optimized acellular nerve for injection in the injured spinal cord.

Spinal cord injury1 linked therapy

2018

PMID 29380912Rat

Ubiquinol treatment for TBI in male rats: Effects on mitochondrial integrity, injury severity, and neurometabolism.

TBI1 linked therapy

2018

PMID 29381633Rat

Evaluation of the Effect of Topical Application of Nigella sativa on Acute Radiation-Induced Nasal Mucositis.

Radiation1 linked therapy

2018

PMID 29382619Rat

The Effects of Memantine on Glutamic Receptor-Associated Nitrosative Stress in a Traumatic Brain Injury Rat Model.

TBI1 linked therapy

2018

PMID 29383878Rat

Functional Outcome of Human Adipose Stem Cell Injections in Rat Anal Sphincter Acute Injury Model.

Wound1 linked therapy

2018

PMID 29385683Rat

Preliminary Characterization, Antioxidant and Hepatoprotective Activities of Polysaccharides from Taishan Pinus massoniana Pollen.

Chemical/toxin1 linked therapy

2018

PMID 29391546Mouse

The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice.

Radiation1 linked therapy

2018

PMID 29393349Rat

Enhancement of tendon-bone healing following rotator cuff repair using hydroxyapatite with TGFbeta1.

Other1 linked therapy

2018

PMID 29394953Mouse

BCN057 induces intestinal stem cell repair and mitigates radiation-induced intestinal injury.

Radiation1 linked therapy

2018

PMID 29398669Rat

Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats.

Haemorrhage/shock1 linked therapy

2018

PMID 29404840Mouse

Lithium Inhibits GSK3beta Activity via Two Different Signaling Pathways in Neurons After Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29408659Rat

Axonal regeneration of different tracts following transplants of human glial restricted progenitors into the injured spinal cord in rats.

Spinal cord injury1 linked therapy

2018

PMID 29415054Mouse

Chitosan oligosaccharide ameliorates acute lung injury induced by blast injury through the DDAH1/ADMA pathway.

Other1 linked therapy

2018

PMID 29417759Rat

Anxiety- and activity-related effects of paracetamol on healthy and neuropathic rats.

Other1 linked therapy

2018

PMID 29431049Rat

Vitamin D supplementation attenuates the behavioral scores of neuropathic pain in rats.

Other1 linked therapy

2018

PMID 29437855Mouse

Identifying the Role of Complement in Triggering Neuroinflammation after Traumatic Brain Injury.

TBI1 linked therapy

2018

PMID 29443855Mouse

Continuous remote ischemic conditioning attenuates cognitive and motor deficits from moderate traumatic brain injury.

TBI1 linked therapy

2018

PMID 29443860Rat

A novel rat model of extremity trauma for prehospital pain management research.

Fracture1 linked therapy

2018

PMID 29446207Rat

VEGF mitigates histone-induced pyroptosis in the remote liver injury associated with renal allograft ischemia-reperfusion injury in rats.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29447233Rat

Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury.

TBI1 linked therapy

2018

PMID 29453815Rat

Chitosan porous 3D scaffolds embedded with resolvin D1 to improve in vivo bone healing.

Fracture1 linked therapy

2018

PMID 29454023Mouse

Interaction between hypothermia and delayed mesenchymal stem cell therapy in neonatal hypoxic-ischemic brain injury.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29455576Mouse

Central Infusion of Insulin-Like Growth Factor-1 Increases Hippocampal Neurogenesis and Improves Neurobehavioral Function after Traumatic Brain Injury.

TBI1 linked therapy

2018

PMID 29456642Rat

Anti-Semaphorin-7A single chain antibody demonstrates beneficial effects on pulmonary inflammation during acute lung injury.

Endotoxin/LPS1 linked therapy

2018

PMID 29457828Mixed

Dihydrodiosgenin protects against experimental acute pancreatitis and associated lung injury through mitochondrial protection and PI3Kgamma/Akt inhibition.

Chemical/toxin1 linked therapy

2018

PMID 29458437Mouse

Ablation of caspase-1 protects against TBI-induced pyroptosis in vitro and in vivo.

TBI1 linked therapy

2018

PMID 29462606Mouse

Limb remote ischemic post-conditioning mitigates brain recovery in a mouse model of ischemic stroke by regulating reactive astrocytic plasticity.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29463096Mouse

Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell Loss.

Radiation1 linked therapy

2018

PMID 29466494Rat

Granulocyte Colony-Stimulating Factor Combined with Methylprednisolone Improves Functional Outcomes in Rats with Experimental Acute Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29466698Rat

ERK1/2/mTOR/Stat3 pathway-mediated autophagy alleviates traumatic brain injury-induced acute lung injury.

TBI1 linked therapy

2018

PMID 29467001Rat

Neuregulin-1 elicits a regulatory immune response following traumatic spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29468968Rat

Arginine Functionalized Bacterial Cellulose Nanofibers Containing Gel as an Effective Wound Dressing: In vitro and In vivo Evaluation.

Wound1 linked therapy

2018

PMID 29478321Mixed

Metabolites of Dietary Acteoside: Profiles, Isolation, Identification, and Hepatoprotective Capacities.

Endotoxin/LPS1 linked therapy

2018

PMID 29481398Mouse

beta-Catenin-Dependent Wnt Signaling: A Pathway in Acute Cutaneous Wounding.

Wound1 linked therapy

2018

PMID 29484657Rat

Melatonin provides protection against heat stroke-induced myocardial injury in male rats.

Other1 linked therapy

2018

PMID 29488614Rat

Penehyclidine hydrochloride inhibits TLR4 signaling and inflammation, and attenuates blunt chest trauma and hemorrhagic shock-induced acute lung injury in rats.

Haemorrhage/shock1 linked therapy

2018

PMID 29489916Rat

Protective effects of tiotropium alone or combined with budesonide against cadmium inhalation induced acute neutrophilic pulmonary inflammation in rats.

Chemical/toxin1 linked therapy

2018

PMID 29492766Rat

Protective Effects of Cornel Iridoid Glycoside in Rats After Traumatic Brain Injury.

TBI1 linked therapy

2018

PMID 29494987Rat

Therapeutic effects of Saussurea involucrata injection against severe acute pancreatitis-induced brain injury in rats.

Chemical/toxin1 linked therapy

2018

PMID 29495362Mouse

In Vivo Protective Effects of Nootkatone against Particles-Induced Lung Injury Caused by Diesel Exhaust Is Mediated via the NF-kappaB Pathway.

Chemical/toxin1 linked therapy

2018

PMID 29501673Rat

Lafoensia pacari A. St.-Hil.: Wound healing activity and mechanism of action of standardized hydroethanolic leaves extract.

Wound1 linked therapy

2018

PMID 29504713Mouse

TAK1 mediates excessive autophagy via p38 and ERK in cisplatin-induced acute kidney injury.

Chemical/toxin1 linked therapy

2018

PMID 29509267Rat

Protective effect of tauroursodeoxycholic acid on the autophagy of nerve cells in rats with acute spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 29510144Rat

Intra-arterial human urinary kallidinogenase alleviates brain injury in rats with permanent middle cerebral artery occlusion through PI3K/AKT/FoxO1 signaling pathway.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29512741Rat

Macrophage migration inhibitory factor antagonist (S,R)3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid methyl ester attenuates inflammation and lung injury in rats with acute pancreatitis in pregnancy.

Chemical/toxin1 linked therapy

2018

PMID 29513816Rat

Effects of aquaporin 4 and inward rectifier potassium channel 4.1 on medullospinal edema after methylprednisolone treatment to suppress acute spinal cord injury in rats.

Spinal cord injury1 linked therapy

2018

PMID 29529001Rat

Synchrotron Radiation Imaging Reveals the Role of Estrogen in Promoting Angiogenesis After Acute Spinal Cord Injury in Rats.

Spinal cord injury1 linked therapy

2018

PMID 29535009Mouse

Sulfated zwitterionic poly(sulfobetaine methacrylate) hydrogels promote complete skin regeneration.

Wound1 linked therapy

901–950 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.