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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

Year Sort by Reset

Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2018

PMID 28549109Mouse

IL-18 cleavage triggers cardiac inflammation and fibrosis upon beta-adrenergic insult.

Chemical/toxin1 linked therapy

2018

PMID 28767631Rat

Neuroprotective Effects of C-terminal Domain of Tetanus Toxin on Rat Brain Against Motorneuron Damages After Experimental Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 28837532Rat

Hyperbaric Oxygen Therapy After Acute Thoracic Spinal Cord Injury: Improvement of Locomotor Recovery in Rats.

Spinal cord injury1 linked therapy

2018

PMID 28930945Rat

Effects of propranolol and clonidine on brain edema, blood-brain barrier permeability, and endothelial glycocalyx disruption after fluid percussion brain injury in the rat.

TBI1 linked therapy

2018

PMID 29016737Mouse

Diverging effects of enalapril or eplerenone in primary prevention against doxorubicin-induced cardiotoxicity.

Chemical/toxin1 linked therapy

2018

PMID 29039895Rat

Effects of Copaiba oil in the healing process of urinary bladder in rats.

Wound1 linked therapy

2018

PMID 29047150Mouse

Rebamipide alleviates radiation-induced colitis through improvement of goblet cell differentiation in mice.

Radiation1 linked therapy

2018

PMID 29049608Rat

Acute administration of oestradiol or progesterone in a spinal cord ischaemia-reperfusion model in rats.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29112734Mixed

Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses.

Radiation1 linked therapy

2018

PMID 29117762Mouse

A Time Limit for Initiating Anti-Inflammatory Treatment for Improved Olfactory Function after Head Injury.

Other1 linked therapy

2018

PMID 29159695Rat

A novel lignin-based nanofibrous dressing containing arginine for wound-healing applications.

Wound1 linked therapy

2018

PMID 29187582Rat

Zhenbao pill protects against acute spinal cord injury via regulating the expression of GPR17.

Spinal cord injury1 linked therapy

2018

PMID 29194316Mixed

Tubastatin A prevents hemorrhage-induced endothelial barrier dysfunction.

Haemorrhage/shock1 linked therapy

2018

PMID 29228863Rat

Parallel Evaluation of Two Potassium Channel Blockers in Restoring Conduction in Mechanical Spinal Cord Injury in Rat.

Spinal cord injury1 linked therapy

2018

PMID 29251705Rat

Human adipose-derived stem cell treatment modulates cellular protection in both in vitro and in vivo traumatic brain injury models.

TBI1 linked therapy

2018

PMID 29251710Mouse

Mesenchymal stem cell-derived extracellular vesicles attenuate pulmonary vascular permeability and lung injury induced by hemorrhagic shock and trauma.

Haemorrhage/shock1 linked therapy

2018

PMID 29266061Mouse

Endogenous calcitonin gene-related peptide suppresses ischemic brain injuries and progression of cognitive decline.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29266409Mouse

Attenuated accumulation of regulatory T cells and reduced production of interleukin 10 lead to the exacerbation of tissue injury in a mouse model of acute respiratory distress syndrome.

Endotoxin/LPS1 linked therapy

2018

PMID 29266693Rat

Injectable hydroxyphenyl derivative of hyaluronic acid hydrogel modified with RGD as scaffold for spinal cord injury repair.

Spinal cord injury1 linked therapy

2018

PMID 29279015Rat

Rodent Neural Progenitor Cells Support Functional Recovery after Cervical Spinal Cord Contusion.

Spinal cord injury1 linked therapy

2018

PMID 29294256Rat

Protective effect of hydroxysafflor yellow A on bleomycin-induced pulmonary inflammation and fibrosis in rats.

Chemical/toxin1 linked therapy

2018

PMID 29299822Mouse

Necrostatin-1 Protects Against Paraquat-Induced Cardiac Contractile Dysfunction via RIP1-RIP3-MLKL-Dependent Necroptosis Pathway.

Chemical/toxin1 linked therapy

2018

PMID 29303018Rat

The beta-adrenoceptor agonist clenbuterol reduces the neuroinflammatory response, neutrophil infiltration and apoptosis following intra-striatal IL-1beta administration to rats.

Other1 linked therapy

2018

PMID 29303417Mouse

Evaluation of Detergent-Free and Detergent-Based Methods for Decellularization of Murine Skin.

Wound1 linked therapy

2018

PMID 29306510Rat

Protective effects of Artemisia campestris extract against gastric acid reflux-induced esophageal mucosa injuries.

Other1 linked therapy

2018

PMID 29306704Mouse

Neuroprotective effect of acute ethanol intoxication in TBI is associated to the hierarchical modulation of early transcriptional responses.

TBI1 linked therapy

2018

PMID 29309057Mouse

Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury.

Crush1 linked therapy

2018

PMID 29316847Rat

Chloroquine Promotes the Recovery of Acute Spinal Cord Injury by Inhibiting Autophagy-Associated Inflammation and Endoplasmic Reticulum Stress.

Spinal cord injury1 linked therapy

2018

PMID 29323194Rat

Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Modify Microglial Response and Improve Clinical Outcomes in Experimental Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29328408Rat

Genistein attenuates di-(2-ethylhexyl) phthalate-induced testicular injuries via activation of Nrf2/HO-1 following prepubertal exposure.

Chemical/toxin1 linked therapy

2018

PMID 29330743Rat

Acute downregulation of miR-155 leads to a reduced collagen synthesis through attenuating macrophages inflammatory factor secretion by targeting SHIP1.

Burn1 linked therapy

2018

PMID 29331644Mouse

Ozone exposure induces respiratory barrier biphasic injury and inflammation controlled by IL-33.

Chemical/toxin1 linked therapy

2018

PMID 29336204Rat

Continuous Infusion of Phenelzine, Cyclosporine A, or Their Combination: Evaluation of Mitochondrial Bioenergetics, Oxidative Damage, and Cytoskeletal Degradation following Severe Controlled Cortical Impact Traumatic Brain Injury in Rats.

TBI1 linked therapy

2018

PMID 29336631Rat

The Beneficial Radioprotective Effect of Tomato Seed Oil Against Gamma Radiation-Induced Damage in Male Rats.

Radiation1 linked therapy

2018

PMID 29343843Mouse

Cathelicidin-OA1, a novel antioxidant peptide identified from an amphibian, accelerates skin wound healing.

Wound1 linked therapy

2018

PMID 29348096Rat

Antiulcer activity of methanol-chloroform extract of Channa striatus fillet.

Chemical/toxin1 linked therapy

2018

PMID 29351405Mouse

Acute downregulation of miR-199a attenuates sepsis-induced acute lung injury by targeting SIRT1.

Endotoxin/LPS1 linked therapy

2018

PMID 29353106Rat

Perineurium-like sheath derived from long-term surviving mesenchymal stem cells confers nerve protection to the injured spinal cord.

Spinal cord injury1 linked therapy

2018

PMID 29355394Rat

The Investigation of the Cox-2 Selective Inhibitor Parecoxib Effects in Spinal Cord Injury in Rat.

Spinal cord injury1 linked therapy

2018

PMID 29357041Rat

Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs.

Other1 linked therapy

2018

PMID 29357739Rat

Grafts of Olfactory Stem Cells Restore Breathing and Motor Functions after Rat Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29357846Mouse

Neoboutonia melleri var velutina Prain: in vitro and in vivo hepatoprotective effects of the aqueous stem bark extract on acute hepatitis models.

Chemical/toxin1 linked therapy

2018

PMID 29358697Rat

Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation.

Crush1 linked therapy

2018

PMID 29360450Rat

Noninvasive, targeted gene therapy for acute spinal cord injury using LIFU-mediated BDNF-loaded cationic nanobubble destruction.

Spinal cord injury1 linked therapy

2018

PMID 29363200Mouse

Optogenetically enhanced axon regeneration: motor versus sensory neuron-specific stimulation.

Other1 linked therapy

2018

PMID 29370063Rat

Fresh whole blood resuscitation does not exacerbate skeletal muscle edema and long-term functional deficit after ischemic injury and hemorrhagic shock.

Ischaemia-reperfusion1 linked therapy

2018

PMID 29372883Mouse

Brain repair by hematopoietic growth factors in the subacute phase of traumatic brain injury.

TBI1 linked therapy

2018

PMID 29373460Mouse

Early low-anticoagulant desulfated heparin after traumatic brain injury: Reduced brain edema and leukocyte mobilization is associated with improved watermaze learning ability weeks after injury.

TBI1 linked therapy

2018

PMID 29373946Rat

Safety and Efficacy of Rose Bengal Derivatives for Glial Scar Ablation in Chronic Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 29373948Rat

Traumatic Brain Injury Disrupts Pain Signaling in the Brainstem and Spinal Cord.

TBI1 linked therapy

851–900 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.