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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2020

PMID 32913497Rat

An injectable liposome for sustained release of tanshinone IIA to the treatment of acute blunt muscle injury by augmenting autophagy and alleviating oxidative stress.

Crush1 linked therapy

2020

PMID 32915636Rat

The protective effects of C16 peptide and angiopoietin-1 compound in lipopolysaccharide-induced acute respiratory distress syndrome.

Endotoxin/LPS1 linked therapy

2020

PMID 32916198Rat

Anti-biofilm and wound-healing activity of chitosan-immobilized Ficin.

Wound1 linked therapy

2020

PMID 32920515Rat

Crocin ameliorates arsenic trioxide-induced cardiotoxicity via Keap1-Nrf2/HO-1 pathway: Reducing oxidative stress, inflammation, and apoptosis.

Chemical/toxin1 linked therapy

2020

PMID 32929341Mixed

Me6TREN targets beta-catenin signaling to stimulate intestinal stem cell regeneration after radiation.

Radiation1 linked therapy

2020

PMID 32934763Mouse

Polydatin Attenuates 14.1 MeV Neutron-Induced Injuries via Regulating the Apoptosis and Antioxidative Pathways and Improving the Hematopoiesis of Mice.

Radiation1 linked therapy

2020

PMID 32934963Mouse

Irisin Pretreatment Protects Kidneys against Acute Kidney Injury Induced by Ischemia/Reperfusion via Upregulating the Expression of Uncoupling Protein 2.

Ischaemia-reperfusion1 linked therapy

2020

PMID 32936496Mouse

Treadmill running initiation times and bone-tendon interface repair in a murine rotator cuff repair model.

Other1 linked therapy

2020

PMID 32938565Mouse

Vitamin D3 analogue facilitates epithelial wound healing through promoting epithelial-mesenchymal transition via the Hippo pathway.

Wound1 linked therapy

2020

PMID 32938916Mouse

Deregulated immune cell recruitment orchestrated by FOXM1 impairs human diabetic wound healing.

Wound1 linked therapy

2020

PMID 32939783Mixed

Melatonin promotes regeneration of injured motor axons via MTreceptors.

Crush1 linked therapy

2020

PMID 32947005Rat

The effects of walking training onset on motor evoked potentials after acute spinal cord injury.

Spinal cord injury1 linked therapy

2020

PMID 32949564Mouse

miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes.

Wound1 linked therapy

2020

PMID 32949571Rat

Ampakines stimulate phrenic motor output after cervical spinal cord injury.

Spinal cord injury1 linked therapy

2020

PMID 32951003Mouse

(+)-Clausenamide protects against drug-induced liver injury by inhibiting hepatocyte ferroptosis

Chemical/toxin1 linked therapy

2020

PMID 32953883Mouse

The Effect of MicroRNA-101 on Angiogenesis of Human Umbilical Vein Endothelial Cells during Hypoxia and in Mice with Myocardial Infarction

Ischaemia-reperfusion1 linked therapy

2020

PMID 32955722Mouse

Acute Traumatic Brain Injury-Induced Neuroinflammatory Response and Neurovascular Disorders in the Brain

TBI1 linked therapy

2020

PMID 32962326Mouse

Direct Peritoneal Resuscitation Improves Survival in a Murine Model of Combined Hemorrhage and Burn Injury

Haemorrhage/shock1 linked therapy

2020

PMID 32962528Rat

Harnessing the Secretome of Mesenchymal Stromal Cells for Traumatic Spinal Cord Injury: Multicell Comparison and Assessment of In Vivo Efficacy

Spinal cord injury1 linked therapy

2020

PMID 32963692Mouse

A Sphingosine-1-Phosphate Receptor Modulator Attenuated Secondary Brain Injury and Improved Neurological Functions of Mice after ICH

Haemorrhage/shock1 linked therapy

2020

PMID 32964904Mixed

A multifunctional shape-adaptive and biodegradable hydrogel with hemorrhage control and broad-spectrum antimicrobial activity for wound healing.

Haemorrhage/shock1 linked therapy

2020

PMID 32967743Rat

TAK-242 Attenuates Crush Injury Induced Acute Kidney Injury through Inhibiting TLR4/NF-kB Signaling Pathways in Rats.

Crush1 linked therapy

2020

PMID 32974320Mouse

Human Salivary Histatin-1 Is More Efficacious in Promoting Acute Skin Wound Healing Than Acellular Dermal Matrix Paste

Wound1 linked therapy

2020

PMID 32977957Mouse

Efficacy of acute administration of inhaled argon on traumatic brain injury in mice.

TBI1 linked therapy

2020

PMID 32979558Rat

Ameliorative effect of AT2R and ACE2 activation on ischemic renal injury associated cardiac and hepatic dysfunction.

Ischaemia-reperfusion1 linked therapy

2020

PMID 32985332Rat

Prophylactic Faecalibacterium prausnitzii treatment prevents the acute breakdown of colonic epithelial barrier in a preclinical model of pelvic radiation disease

Radiation1 linked therapy

2020

PMID 32987768Rat

Docosahexaenoic Acid-Loaded Polylactic Acid Core-Shell Nanofiber Membranes for Regenerative Medicine after Spinal Cord Injury: In Vitro and In Vivo Study

Spinal cord injury1 linked therapy

2020

PMID 32990006Rat

Resveratrol ameliorates hepatic injury and modulates hepatic biomarkers of regeneration, apoptosis and survival in a rat model of blunt hepatic trauma.

Crush1 linked therapy

2020

PMID 32994005Rat

Polyurethane/carboxymethylcellulose nanofibers containing Malva sylvestris extract for healing diabetic wounds: Preparation, characterization, in vitro and in vivo studies.

Wound1 linked therapy

2020

PMID 32996916Mouse

Transplantation of insulin-like growth factor-1 laden scaffolds combined with exercise promotes neuroregeneration and angiogenesis in a preclinical muscle injury model.

Wound1 linked therapy

2020

PMID 33004081Mouse

The protective effect of L-glutamine against acute Cantharidin-induced Cardiotoxicity in the mice.

Chemical/toxin1 linked therapy

2020

PMID 33007822Rat

Hyperbaric Oxygen Treatment Following Mid-Cervical Spinal Cord Injury Preserves Diaphragm Muscle Function.

Spinal cord injury1 linked therapy

2020

PMID 33008033Rat

Protective Effects of Simvastatin on Endotoxin-Induced Acute Kidney Injury through Activation of Tubular Epithelial Cells' Survival and Hindering Cytochrome C-Mediated Apoptosis.

Endotoxin/LPS1 linked therapy

2020

PMID 33009888Mouse

Exosomes from miRNA-126-modified endothelial progenitor cells alleviate brain injury and promote functional recovery after stroke.

Ischaemia-reperfusion1 linked therapy

2020

PMID 33017574Mouse

Autotaxin inhibition reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction.

Ischaemia-reperfusion1 linked therapy

2020

PMID 33028617Mouse

Human Gut Commensal Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells.

Wound1 linked therapy

2020

PMID 33037560Rat

Photobiomodulation therapy on expression of HSP70 protein and tissue repair in experimental acute Achilles tendinitis.

Chemical/toxin1 linked therapy

2020

PMID 33038830Mouse

Acute injection of a DHA triglyceride emulsion after hypoxic-ischemic brain injury in mice increases both DHA and EPA levels in blood and brain.

Ischaemia-reperfusion1 linked therapy

2020

PMID 33042267Mixed

Toll-like receptor 5 deficiency diminishes doxorubicin-induced acute cardiotoxicity in mice.

Chemical/toxin1 linked therapy

2020

PMID 33046081Rat

Sphingosine 1-phosphate protects against radiation-induced ovarian injury in female rats-impact on mitochondrial-related genes.

Radiation1 linked therapy

2020

PMID 33049117Rat

COX-2 inhibition does not alter wound healing outcomes of a volumetric muscle loss injury treated with a biologic scaffold.

Other1 linked therapy

2020

PMID 33057080Mouse

A single dose of estrogen during hemorrhagic shock protects against Kidney Injury whereas estrogen restoration in ovariectomized mice is ineffective.

Haemorrhage/shock1 linked therapy

2020

PMID 33061373Rat

Construction of Microunits by Adipose-Derived Mesenchymal Stem Cells Laden with Porous Microcryogels for Repairing an Acute Achilles Tendon Rupture in a Rat Model.

Other1 linked therapy

2020

PMID 33062068Mouse

Wild Bitter Melon Exerts Anti-Inflammatory Effects by Upregulating Injury-Attenuated CISD2 Expression following Spinal Cord Injury.

Spinal cord injury1 linked therapy

2020

PMID 33065363Mouse

Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation.

Chemical/toxin1 linked therapy

2020

PMID 33068795Rat

Non-invasive neuromodulation using rTMS and the electromagnetic-perceptive gene (EPG) facilitates plasticity after nerve injury.

Other1 linked therapy

2020

PMID 33069813Mouse

Spinal caspase-3 contributes to tibial fracture-associated postoperative allodynia via up-regulation of LRRTM1 expression in mice.

Fracture1 linked therapy

2020

PMID 33070393Mixed

Inhibition of ACSL4 attenuates ferroptotic damage after pulmonary ischemia-reperfusion.

Ischaemia-reperfusion1 linked therapy

2020

PMID 33076741Rat

Autophagy Induction Contributes to the Neuroprotective Impact of Intermittent Fasting on the Acutely Injured Spinal Cord.

Spinal cord injury1 linked therapy

2020

PMID 33076989Mouse

Nilvadipine suppresses inflammation via inhibition of P-SYK and restores spatial memory deficits in a mouse model of repetitive mild TBI.

TBI1 linked therapy

301–350 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.