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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

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PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2020

PMID 32698911Mouse

Overexpression of TGFβ1 in murine mesenchymal stem cells improves lung inflammation by impacting the Th17/Treg balance in LPS-induced ARDS mice.

Endotoxin/LPS1 linked therapy

2020

PMID 32705267Rat

Dexmedetomidine alleviates blunt chest trauma and hemorrhagic shock-resuscitation-induced acute lung injury through inhibiting the NLRP3 inflammasome.

Haemorrhage/shock1 linked therapy

2020

PMID 32707897Mouse

Topical Application of Phlorotannins from Brown Seaweed Mitigates Radiation Dermatitis in a Mouse Model.

Radiation1 linked therapy

2020

PMID 32708645Mouse

Effects of Electrospun Fibrous Membranes of PolyCaprolactone and Chitosan/Poly(Ethylene Oxide) on Mouse Acute Skin Lesions.

Wound1 linked therapy

2020

PMID 32709896Rat

Topical cell-free conditioned media harvested from adipose tissue-derived stem cells promote recovery from corneal epithelial defects caused by chemical burns.

Burn1 linked therapy

2020

PMID 32719328Mouse

Mithramycin selectively attenuates DNA-damage-induced neuronal cell death.

TBI1 linked therapy

2020

PMID 32739742Mouse

Therapeutic effect of phycocyanin on acute liver oxidative damage caused by X-ray.

Radiation1 linked therapy

2020

PMID 32746910Rat

Dental follicle stem cells rescue the regenerative capacity of inflamed rat dental pulp through a paracrine pathway.

Endotoxin/LPS1 linked therapy

2020

PMID 32746943Mouse

Mitigative efficacy of the clinical dosage administration of granulocyte colony-stimulating factor and romiplostim in mice with severe acute radiation syndrome.

Radiation1 linked therapy

2020

PMID 32750367Rat

Acute administration of metformin prior to cardiac ischemia/reperfusion injury protects brain injury.

Ischaemia-reperfusion1 linked therapy

2020

PMID 32758490Mouse

Mitochondrial targeted therapy with elamipretide (MTP-131) as an adjunct to tumor necrosis factor inhibition for traumatic optic neuropathy in the acute setting.

TBI1 linked therapy

2020

PMID 32763819Mouse

Temporary blockade of interferon-gamma ameliorates doxorubicin-induced cardiotoxicity without influencing the anti-tumor effect.

Chemical/toxin1 linked therapy

2020

PMID 32784044Mouse

GMP-compliant sponge-like dressing containing MSC lyo-secretome: Proteomic network of healing in a murine wound model.

Wound1 linked therapy

2020

PMID 32791187Mouse

Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-inducer, beta-naphthoflavone (BNF), and differential sex-specific effects.

Other1 linked therapy

2020

PMID 32794246Mouse

Maresin 1 resolves aged-associated macrophage inflammation to improve bone regeneration.

Fracture1 linked therapy

2020

PMID 32794261Mouse

Inducible nitric oxide synthase is required for epidermal permeability barrier homeostasis in mice.

Wound1 linked therapy

2020

PMID 32795555Rat

Mitigation of Microglia-mediated Acute Neuroinflammation and Tissue Damage by Heme Oxygenase 1 in a Rat Spinal Cord Injury Model.

Spinal cord injury1 linked therapy

2020

PMID 32796819Mouse

XJB-5-131 inhibited ferroptosis in tubular epithelial cells after ischemia-reperfusion injury.

Ischaemia-reperfusion1 linked therapy

2020

PMID 32796834Mouse

Upregulation of miR-382 contributes to renal fibrosis secondary to aristolochic acid-induced kidney injury via PTEN signaling pathway.

Chemical/toxin1 linked therapy

2020

PMID 32802873Rat

Nuclear Heme Oxidase-1 Inhibits Endoplasmic Reticulum Stress-Mediated Apoptosis after Spinal Cord Injury.

Spinal cord injury1 linked therapy

2020

PMID 32807453Rat

Molecular mechanism of long-term neuroprotective effects of gradual flow restoration on cerebral ischemia reperfusion injury in MCAO rats.

Ischaemia-reperfusion1 linked therapy

2020

PMID 32814473Mouse

Irisin alleviates LPS-induced liver injury and inflammation through inhibition of NLRP3 inflammasome and NF-kappaB signaling.

Endotoxin/LPS1 linked therapy

2020

PMID 32821743Mouse

Platelet-rich plasma accelerates skin wound healing by promoting re-epithelialization.

Wound1 linked therapy

2020

PMID 32825525Mouse

Inhibition of miRNA-34a Promotes M2 Macrophage Polarization and Improves LPS-Induced Lung Injury by Targeting Klf4.

Endotoxin/LPS1 linked therapy

2020

PMID 32842687Mouse

Biochemical Evaluation of the Antioxidant Effects of Hydroxytyrosol on Pancreatitis-Associated Gut Injury.

Chemical/toxin1 linked therapy

2020

PMID 32849636Mouse

Circulating FH Protects Kidneys From Tubular Injury During Systemic Hemolysis.

Chemical/toxin1 linked therapy

2020

PMID 32852719Rat

Tissue Plasminogen Activator Loaded PCL Nanofibrous Scaffold Promoted Nerve Regeneration After Sciatic Nerve Transection in Male Rats.

Other1 linked therapy

2020

PMID 32853656Mouse

Short-term doxorubicin cardiotoxic effects: involvement of cardiac Thyrotropin Releasing Hormone system.

Chemical/toxin1 linked therapy

2020

PMID 32854778Mouse

Extracellular vesicles derived from mesenchymal stromal cells mitigate intestinal toxicity in a mouse model of acute radiation syndrome.

Radiation1 linked therapy

2020

PMID 32856173Mouse

The Regenerative Effect of Trans-spinal Magnetic Stimulation After Spinal Cord Injury: Mechanisms and Pathways Underlying the Effect.

Spinal cord injury1 linked therapy

2020

PMID 32856486Mouse

MDM2 inhibition improves cisplatin-induced renal injury in mice via inactivation of Notch/hes1 signaling pathway.

Chemical/toxin1 linked therapy

2020

PMID 32858129Mouse

Delayed metformin treatment improves functional recovery following traumatic brain injury via central AMPK-dependent brain tissue repair.

TBI1 linked therapy

2020

PMID 32860604Rat

Bradykinin-Potentiating Activity of a Gamma-Irradiated Bioactive Fraction Isolated from Scorpion (Leiurus quinquestriatus) Venom in Rats with Doxorubicin-Induced Acute Cardiotoxicity: Favorable Modulation of Oxidative Stress and Inflammatory, Fibrogenic and Apoptotic Pathways.

Chemical/toxin1 linked therapy

2020

PMID 32863068Rat

Exogenous insulin-like growth factor 1 attenuates acute ischemic stroke-induced spatial memory impairment via modulating inflammatory response and tau phosphorylation.

Ischaemia-reperfusion1 linked therapy

2020

PMID 32864929Rat

The Role of Vaccinium Myrtillus in the Prevention of Renal Injury in an Experimental Model of Ruptured Abdominal Aortic Aneurysm

Ischaemia-reperfusion1 linked therapy

2020

PMID 32868705Mouse

A Potential Role for Excess Tissue Iron in Development of Cardiovascular Delayed Effects of Acute Radiation Exposure

Radiation1 linked therapy

2020

PMID 32872240Mouse

Dihydrotestosterone (DHT) Enhances Wound Healing of Major Burn Injury by Accelerating Resolution of Inflammation in Mice

Burn1 linked therapy

2020

PMID 32876073Mouse

The Anti-Inflammatory Effect of Trichilia martiana C. DC. in the Lipopolysaccharide-Stimulated Inflammatory Response in Macrophages and Airway Epithelial Cells and in LPS-Challenged Mice

Endotoxin/LPS1 linked therapy

2020

PMID 32876675Rat

Rosiglitazone ameliorates radiation-induced intestinal inflammation in rats by inhibiting NLRP3 inflammasome and TNF-alpha production

Radiation1 linked therapy

2020

PMID 32876761Mouse

Effect of photobiomodulation therapy on radiodermatitis in a mouse model: an experimental animal study.

Radiation1 linked therapy

2020

PMID 32876840Mixed

Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway.

Haemorrhage/shock1 linked therapy

2020

PMID 32881928Mouse

Functional recovery with histomorphometric analysis of nerves and muscles after combination treatment with erythropoietin and dexamethasone in acute peripheral nerve injury.

Crush1 linked therapy

2020

PMID 32883957Mixed

Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy.

Radiation1 linked therapy

2020

PMID 32885586Mouse

Pyrophosphate therapy prevents trauma-induced calcification in the mouse model of neurogenic heterotopic ossification.

TBI1 linked therapy

2020

PMID 32885685Mouse

Protective effects of isorhynchophylline against silicon-dioxide-induced lung injury in mice.

Chemical/toxin1 linked therapy

2020

PMID 32899204Rat

Nephroprotective Effect of Cilastatin against Gentamicin-Induced Renal Injury In Vitro and In Vivo without Altering Its Bactericidal Efficiency.

Chemical/toxin1 linked therapy

2020

PMID 32899913Mouse

Bee Venom Melittin Protects against Cisplatin-Induced Acute Kidney Injury in Mice via the Regulation of M2 Macrophage Activation.

Chemical/toxin1 linked therapy

2020

PMID 32900484Mouse

Serpina3n is closely associated with fibrotic procession and knockdown ameliorates bleomycin-induced pulmonary fibrosis.

Chemical/toxin1 linked therapy

2020

PMID 32901075Mouse

Administration of cardiac mesenchymal cells modulates innate immunity in the acute phase of myocardial infarction in mice.

Ischaemia-reperfusion1 linked therapy

2020

PMID 32908131Rat

Microenvironment-responsive immunoregulatory electrospun fibers for promoting nerve function recovery.

Spinal cord injury1 linked therapy

251–300 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.