Skip to content

RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

Loading the evidence…

Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

Year Sort by Reset

Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2016

PMID 26883642Mouse

Proof-of Concept that an Acute Trophic Factors Intervention After Spinal Cord Injury Provides an Adequate Niche for Neuroprotection, Recruitment of Nestin-Expressing Progenitors and Regeneration.

Spinal cord injury1 linked therapy

2016

PMID 26894518Rat

Imaging and serum biomarkers reflecting the functional efficacy of extended erythropoietin treatment in rats following infantile traumatic brain injury.

TBI1 linked therapy

2016

PMID 26895158Rat

Localized delivery of methylprednisolone sodium succinate with polymeric nanoparticles in experimental injured spinal cord model.

Spinal cord injury1 linked therapy

2016

PMID 26896832Mouse

Rho kinase inhibition following traumatic brain injury in mice promotes functional improvement and acute neuron survival but has little effect on neurogenesis, glial responses or neuroinflammation.

TBI1 linked therapy

2016

PMID 26905096Mouse

Evaluation of the ability of bone marrow derived cells to engraft the kidney and promote renal tubular regeneration in mice following exposure to cisplatin.

Chemical/toxin1 linked therapy

2016

PMID 26914130Rat

Sivelestat sodium hydrate attenuates acute lung injury by decreasing systemic inflammation in a rat model of severe burns.

Burn1 linked therapy

2016

PMID 26914600Rat

A hybrid microfluidic system for regulation of neural differentiation in induced pluripotent stem cells.

Spinal cord injury1 linked therapy

2016

PMID 26923363Mouse

Dexamethasone retrodialysis attenuates microglial response to implanted probes in vivo.

TBI1 linked therapy

2016

PMID 26931747Rat

Transplantation of bone marrow-derived mesenchymal stem cells (BMSCs) improves brain ischemia-induced pulmonary injury in rats associated to TNF-alpha expression.

Ischaemia-reperfusion1 linked therapy

2016

PMID 26945982Mouse

Chrysophyllum cainito leaves are effective against pre-clinical chronic pain models: Analysis of crude extract, fraction and isolated compounds in mice.

Other1 linked therapy

2016

PMID 26948004Rat

Delayed administration of recombinant human parathyroid hormone improves early biomechanical strength in a rat rotator cuff repair model.

Other1 linked therapy

2016

PMID 26958814Rat

A novel composite type I collagen scaffold with micropatterned porosity regulates the entrance of phagocytes in a severe model of spinal cord injury.

Spinal cord injury1 linked therapy

2016

PMID 26967557Mixed

MG53 permeates through blood-brain barrier to protect ischemic brain injury.

Ischaemia-reperfusion1 linked therapy

2016

PMID 26967696Rat

(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology.

Other1 linked therapy

2016

PMID 26969621Mouse

Intracerebroventricular administration of chondroitinase ABC reduces acute edema after traumatic brain injury in mice.

TBI1 linked therapy

2016

PMID 26970185Rat

Therapeutic effects of antigen affinity-purified polyclonal anti-receptor of advanced glycation end-product (RAGE) antibodies on cholestasis-induced liver injury in rats.

Other1 linked therapy

2016

PMID 26976407Rat

Evaluation of conventional therapeutic methods versus maggot therapy in the evolution of healing of tegumental injuries in Wistar rats with and without diabetes mellitus.

Wound1 linked therapy

2016

PMID 26978580Mouse

Combination of microRNA-21 and microRNA-146a Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction in Mice.

Ischaemia-reperfusion1 linked therapy

2016

PMID 26979865Mouse

Exendin-4 Inhibits Matrix Metalloproteinase-9 Activation and Reduces Infarct Growth After Focal Cerebral Ischemia in Hyperglycemic Mice.

Ischaemia-reperfusion1 linked therapy

2016

PMID 26980009Mouse

Blocking B7-1/CD28 Pathway Diminished Long-Range Brain Damage by Regulating the Immune and Inflammatory Responses in a Mouse Model of Intracerebral Hemorrhage.

Other1 linked therapy

2016

PMID 26983894Rat

Low-level laser therapy attenuates the acute inflammatory response induced by muscle traumatic injury.

Crush1 linked therapy

2016

PMID 26990366Mouse

Remote ischemic conditioning protects against acetaminophen-induced acute liver injury in mice.

Chemical/toxin1 linked therapy

2016

PMID 27003408Rat

Assessment of Glial Scar, Tissue Sparing, Behavioral Recovery and Axonal Regeneration following Acute Transplantation of Genetically Modified Human Umbilical Cord Blood Cells in a Rat Model of Spinal Cord Contusion.

Spinal cord injury1 linked therapy

2016

PMID 27007335Mouse

Somatostatin Reduces the Acute Lung Injury of Mice via Increasing the Affinity of Glucocorticoid Receptor.

Chemical/toxin1 linked therapy

2016

PMID 27009445Rat

Exogenous Neuritin Promotes Nerve Regeneration After Acute Spinal Cord Injury in Rats.

Spinal cord injury1 linked therapy

2016

PMID 27013672Rat

Sleep Modulation Alleviates Axonal Damage and Cognitive Decline after Rodent Traumatic Brain Injury.

TBI1 linked therapy

2016

PMID 27018061Rat

Adrenergic activation attenuates astrocyte swelling induced by hypotonicity and neurotrauma.

Spinal cord injury1 linked therapy

2016

PMID 27027557Mouse

Intraluminal tranexamic acid inhibits intestinal sheddases and mitigates gut and lung injury and inflammation in a rodent model of hemorrhagic shock.

Haemorrhage/shock1 linked therapy

2016

PMID 27035345Mouse

Effects of Topically Applied Vitamin D during Corneal Wound Healing.

Wound1 linked therapy

2016

PMID 27037275Rat

Enhanced protection against renal ischemia-reperfusion injury with combined melatonin and exendin-4 in a rodent model.

Ischaemia-reperfusion1 linked therapy

2016

PMID 27043523Mouse

Silymarin Prevents Restraint Stress-Induced Acute Liver Injury by Ameliorating Oxidative Stress and Reducing Inflammatory Response.

Other1 linked therapy

2016

PMID 27043916Mouse

Targeting coagulation factor XII as a novel therapeutic option in brain trauma.

TBI1 linked therapy

2016

PMID 27050785Rat

The effect of amifostine on bacterial translocation after radiation induced acute enteritis.

Radiation1 linked therapy

2016

PMID 27052416Mouse

Activated protein C protects against renal ischaemia/reperfusion injury, independent of its anticoagulant properties.

Ischaemia-reperfusion1 linked therapy

2016

PMID 27052452Rat

Protective effect of Naringin on experimental hindlimb ischemia/reperfusion injury in rats.

Ischaemia-reperfusion1 linked therapy

2016

PMID 27055556Rat

Naloxone pretreatment prevents kidney injury after liver ischemia reperfusion injury.

Ischaemia-reperfusion1 linked therapy

2016

PMID 27059390Rat

Pyruvate treatment attenuates cerebral metabolic depression and neuronal loss after experimental traumatic brain injury.

TBI1 linked therapy

2016

PMID 27060873Rat

Mitigation of sensory and motor deficits by acrolein scavenger phenelzine in a rat model of spinal cord contusive injury.

Spinal cord injury1 linked therapy

2016

PMID 27061967Rat

Bone-marrow-derived mesenchymal stem cells inhibit gastric aspiration lung injury and inflammation in rats.

Chemical/toxin1 linked therapy

2016

PMID 27067456Mouse

A synthetic biology-based device prevents liver injury in mice.

Chemical/toxin1 linked therapy

2016

PMID 27067657Rat

Dopamine D1 receptor agonist A-68930 inhibits NLRP3 inflammasome activation and protects rats from spinal cord injury-induced acute lung injury.

Spinal cord injury1 linked therapy

2016

PMID 27072584Rat

Protective effects of alpha lipoic acid on radiation-induced salivary gland injury in rats.

Radiation1 linked therapy

2016

PMID 27075766Mouse

Expansion and Hepatic Differentiation of Adult Blood-Derived CD34+ Progenitor Cells and Promotion of Liver Regeneration After Acute Injury.

Chemical/toxin1 linked therapy

2016

PMID 27077886Rat

delta-Ctenitoxin-Pn1a, a Peptide from Phoneutria nigriventer Spider Venom, Shows Antinociceptive Effect Involving Opioid and Cannabinoid Systems, in Rats.

Other1 linked therapy

2016

PMID 27079999Rat

Enhanced recovery of breathing capacity from combined adenosine 2A receptor inhibition and daily acute intermittent hypoxia after chronic cervical spinal injury.

Spinal cord injury1 linked therapy

2016

PMID 27082939Mouse

Geranylgeranylacetone alleviates radiation-induced lung injury by inhibiting epithelial-to-mesenchymal transition signaling.

Radiation1 linked therapy

2016

PMID 27085942Rat

The study of traditional Chinese medical elongated-needle therapy promoting neurological recovery mechanism after spinal cord injury in rats.

Spinal cord injury1 linked therapy

2016

PMID 27087602Rat

The selective sigma-1 receptor antagonist E-52862 attenuates neuropathic pain of different aetiology in rats.

Other1 linked therapy

2016

PMID 27090977Guinea pig

Nondermal irritating hyperosmotic nanoemulsions reduce treatment times in a contamination model of wound healing.

Wound1 linked therapy

2016

PMID 27096857Rat

Effect of Hevea brasiliensis latex sap gel on healing of acute skin wounds induced on the back of rats.

Wound1 linked therapy

1,701–1,750 of 4,095

PreviousPage 35 of 82Next

The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.