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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

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PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

Year Sort by Reset

Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2017

PMID 29290051Rat

Protective Effects of Selenium on Cyclophosphamide-Induced Oxidative Stress and Kidney Injury.

Chemical/toxin1 linked therapy

2017

PMID 29290653Rat

Pharmacokinetics and pharmacodynamics of Shengjiang decoction in rats with acute pancreatitis for protecting against multiple organ injury.

Chemical/toxin1 linked therapy

2017

PMID 29311915Mouse

Total Coumarins from Hydrangea paniculata Show Renal Protective Effects in Lipopolysaccharide-Induced Acute Kidney Injury via Anti-inflammatory and Antioxidant Activities.

Endotoxin/LPS1 linked therapy

2017

PMID 29442452Rat

The neuroprotective effect of N-acetylcysteine in spinal cord-injured rats.

Spinal cord injury1 linked therapy

2017

PMID 29445744Rat

Simvastatin Ameliorates PAK4 Inhibitor-Induced Gut and Lung Injury.

Chemical/toxin1 linked therapy

2017

PMID 30023761Rat

Scarless Wound Closure by a Mussel-Inspired Poly(amidoamine) Tissue Adhesive with Tunable Degradability.

Wound1 linked therapy

2017

PMID 31048996Rat

Studies on wound healing potential of red pigment isolated from marine Bacteriumsp.

Wound1 linked therapy

2016

PMID 25000248Rat

Effects of 3-aminobenzamide on ventricular function in infarct heart assessed by quantitative tissue velocity imaging.

Ischaemia-reperfusion1 linked therapy

2016

PMID 26317567Mouse

Posttraumatic Propofol Neurotoxicity Is Mediated via the Pro-Brain-Derived Neurotrophic Factor-p75 Neurotrophin Receptor Pathway in Adult Mice.

TBI1 linked therapy

2016

PMID 26410851Mouse

Piperine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Modulating NF-kappaB Signaling Pathways.

Endotoxin/LPS1 linked therapy

2016

PMID 26454446Rat

Erythropoietin Pretreatment Attenuates Seawater Aspiration-Induced Acute Lung Injury in Rats.

Other1 linked therapy

2016

PMID 26509319Rat

Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2.

Burn1 linked therapy

2016

PMID 26521252Rat

Erythropoietin Protects Rat Brain Injury from Carbon Monoxide Poisoning by Inhibiting Toll-Like Receptor 4/NF-kappa B-Dependent Inflammatory Responses.

Chemical/toxin1 linked therapy

2016

PMID 26540149Rat

Neuromuscular Blocking Agent Cisatracurium Attenuates Lung Injury by Inhibition of Nicotinic Acetylcholine Receptor-alpha1.

Chemical/toxin1 linked therapy

2016

PMID 26662641Rat

Administration of low dose estrogen attenuates gliosis and protects neurons in acute spinal cord injury in rats.

Spinal cord injury1 linked therapy

2016

PMID 26670109Mouse

Does enoxaparin interfere with HMGB1 signaling after TBI? A potential mechanism for reduced cerebral edema and neurologic recovery.

TBI1 linked therapy

2016

PMID 26671075Rat

Cyclosporine Treatment in Traumatic Brain Injury: Operation Brain Trauma Therapy.

TBI1 linked therapy

2016

PMID 26715414Mouse

Beneficial Effect of Erythropoietin Short Peptide on Acute Traumatic Brain Injury.

TBI1 linked therapy

2016

PMID 26717106Rat

Bone Marrow Mesenchymal Stem Cells Suppress Acute Lung Injury Induced by Lipopolysaccharide Through Inhibiting the TLR2, 4/NF-kappaB Pathway in Rats with Multiple Trauma.

Endotoxin/LPS1 linked therapy

2016

PMID 26732591Rat

Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.

Crush1 linked therapy

2016

PMID 26742649Rat

Effects of lidocaine on torn rotator cuff tendons.

Other1 linked therapy

2016

PMID 26746208Rat

Protective effect of mycophenolate mofetil against nephrotoxicity and hepatotoxicity induced by tacrolimus in Wistar rats.

Chemical/toxin1 linked therapy

2016

PMID 26746866Mouse

Cerebroprotection by the neuronal PGE2 receptor EP2 after intracerebral hemorrhage in middle-aged mice.

Haemorrhage/shock1 linked therapy

2016

PMID 26757855Rat

Traumatic Brain Injury Causes Endothelial Dysfunction in the Systemic Microcirculation through Arginase-1-Dependent Uncoupling of Endothelial Nitric Oxide Synthase.

TBI1 linked therapy

2016

PMID 26758066Mixed

Pharmacological reports about gastroprotective effects of methanolic extract from leaves of Solidago chilensis (Brazilian arnica) and its components quercitrin and afzelin in rodents.

Chemical/toxin1 linked therapy

2016

PMID 26768879Rat

The Effects of Adipose Tissue-Derived Mesenchymal Stem Cell Transplantation During the Acute and Subacute Phases Following Spinal Cord Injury.

Spinal cord injury1 linked therapy

2016

PMID 26769343Rat

Epidermal growth factor attenuates blood-spinal cord barrier disruption via PI3K/Akt/Rac1 pathway after acute spinal cord injury.

Spinal cord injury1 linked therapy

2016

PMID 26772189Rat

Epoxyeicosatrienoic acid analogue mitigates kidney injury in a rat model of radiation nephropathy.

Radiation1 linked therapy

2016

PMID 26772988Mouse

Delayed application of the haematopoietic growth factors G-CSF/SCF and FL reduces neonatal excitotoxic brain injury.

Other1 linked therapy

2016

PMID 26779806Rat

Application of Allogeneic Fibroblast Cultured on Acellular Amniotic Membrane for Full-thickness Wound Healing in Rats.

Wound1 linked therapy

2016

PMID 26783184Mouse

IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo.

Chemical/toxin1 linked therapy

2016

PMID 26785976Rat

Acute versus chronic phase mechanisms in a rat model of CRPS.

Fracture1 linked therapy

2016

PMID 26787859Mouse

Beneficial effects of IL-37 after spinal cord injury in mice.

Spinal cord injury1 linked therapy

2016

PMID 26795599Mouse

Sinomenine activation of Nrf2 signaling prevents hyperactive inflammation and kidney injury in a mouse model of obstructive nephropathy.

Other1 linked therapy

2016

PMID 26797017Mouse

Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription.

Chemical/toxin1 linked therapy

2016

PMID 26798045Rat

Changes in serum cytokine levels, hepatic and intestinal morphology in aflatoxin B1-induced injury: modulatory roles of melatonin and flavonoid-rich fractions from Chromolena odorata.

Chemical/toxin1 linked therapy

2016

PMID 26801304Rat

Targeted delivery of human iPS-ECs overexpressing IL-8 receptors inhibits neointimal and inflammatory responses to vascular injury in the rat.

Other1 linked therapy

2016

PMID 26808574Mouse

IL-10 Accelerates Re-Endothelialization and Inhibits Post-Injury Intimal Hyperplasia following Carotid Artery Denudation.

Other1 linked therapy

2016

PMID 26822402Rat

Neuroprotective Effects of Hydrogen Sulfide Against Early Brain Injury and Secondary Cognitive Deficits Following Subarachnoid Hemorrhage.

Haemorrhage/shock1 linked therapy

2016

PMID 26825312Rat

Minocycline Transiently Reduces Microglia/Macrophage Activation but Exacerbates Cognitive Deficits Following Repetitive Traumatic Brain Injury in the Neonatal Rat.

TBI1 linked therapy

2016

PMID 26843634Rat

Blockade of Astrocytic Calcineurin/NFAT Signaling Helps to Normalize Hippocampal Synaptic Function and Plasticity in a Rat Model of Traumatic Brain Injury.

TBI1 linked therapy

2016

PMID 26845156Rat

Gastroprotective Effects of Astragaloside IV against Acute Gastric Lesion in Rats.

Other1 linked therapy

2016

PMID 26852702Rat

Transplantation of neural progenitor cells in chronic spinal cord injury.

Spinal cord injury1 linked therapy

2016

PMID 26852757Rat

The Effect of the iNOS Inhibitor S-Methylisothiourea and Hyperbaric Oxygen Treatment on Radiation Colitis in Rats.

Radiation1 linked therapy

2016

PMID 26855944Rat

Effects of methylene blue in acute lung injury induced by oleic acid in rats.

Chemical/toxin1 linked therapy

2016

PMID 26871438Mouse

MW151 Inhibited IL-1beta Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses.

TBI1 linked therapy

2016

PMID 26872699Mouse

Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells.

Other1 linked therapy

2016

PMID 26873500Rat

Light-emitting diode therapy increases collagen deposition during the repair process of skeletal muscle.

Other1 linked therapy

2016

PMID 26880229Mouse

Targeted activation of CREB in reactive astrocytes is neuroprotective in focal acute cortical injury.

TBI1 linked therapy

2016

PMID 26880298Mouse

Timing of excision after a non-severe burn has a significant impact on the subsequent immune response in a murine model.

Burn1 linked therapy

1,651–1,700 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.