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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

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PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2018

PMID 30584925Rat

Inflammatory cytokines are involved in dihydrocapsaicin (DHC) and regional cooling infusion (RCI)-induced neuroprotection in ischemic rat.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30590196Mouse

Tabebuia aurea decreases hyperalgesia and neuronal injury induced by snake venom.

Chemical/toxin1 linked therapy

2018

PMID 30591020Rat

Thrombin contributes to the injury development and neurological deficit after acute subdural hemorrhage in rats only in collaboration with additional blood-derived factors.

Haemorrhage/shock1 linked therapy

2018

PMID 30602693Mouse

Hepatoprotective Effect of Baicalein Against Acetaminophen-Induced Acute Liver Injury in Mice.

Chemical/toxin1 linked therapy

2018

PMID 30605745Mouse

Radioprotective effect of Hohenbuehelia serotina polysaccharides through mediation of ER apoptosis pathway in vivo.

Radiation1 linked therapy

2018

PMID 30622431Mouse

The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling.

Chemical/toxin1 linked therapy

2018

PMID 30624514Rat

Influence of tramadol on functional recovery of acute spinal cord injury in rats.

Spinal cord injury1 linked therapy

2018

PMID 30627586Rat

Neuroprotection by Paeoniflorin against Nuclear Factor Kappa B-Induced Neuroinflammation on Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 30632675Rat

Activation of AMPK alleviates cardiopulmonary bypass-induced cardiac injury via ameliorating acute cardiac glucose metabolic disorder.

Other1 linked therapy

2018

PMID 30643385Mouse

Xyloketal derivative C53N protects against mild traumatic brain injury in mice.

TBI1 linked therapy

2018

PMID 30651871Rat

Effects of altitude changes on mild-to-moderate closed-head injury in rats following acute high-altitude exposure.

TBI1 linked therapy

2018

PMID 30680187Mouse

Hepatoprotective effects of blue honeysuckle on CCl4-induced acute liver damaged mice.

Chemical/toxin1 linked therapy

2018

PMID 30686001Rat

Evaluation of the effect of BMSCs condition media and methylprednisolone in TGF-beta expression and functional recovery after an acute spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 30687812Mouse

Oral Ibuprofen Interferes with Cellular Healing Responses in a Murine Model of Achilles Tendinopathy.

Other1 linked therapy

2018

PMID 30691831Rat

Effect of Hydrogen Sulfide on Kidney Injury in Rat Model of Crush Syndrome.

Crush1 linked therapy

2018

PMID 30713662Mouse

Diallyl sulfide treatment protects against acetaminophen-/carbon tetrachloride-induced acute liver injury by inhibiting oxidative stress, inflammation and apoptosis in mice.

Chemical/toxin1 linked therapy

2018

PMID 30825974Mouse

1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer's patch-associated regenerating crypts in the small intestines after radiation injury.

Radiation1 linked therapy

2018

PMID 31048987Rat

Anti-inflammatory, antioxidant and antihepatotoxic effects ofagainst d-galactosamine induced hepatotoxicity in rats.

Chemical/toxin1 linked therapy

2018

PMID 31353538Mouse

Vitex agnus-castus safeguards the lung against lipopolysaccharide-induced toxicity in mice.

Endotoxin/LPS1 linked therapy

2018

PMID 31435346Rat

Hepatoprotective effect of hydromethanolic leaf extract of (Urticaceae) on carbon tetrachloride-induced liver injury and oxidative stress.

Chemical/toxin1 linked therapy

2018

PMID 32186134Mouse

Effect of Yupingfeng granules on the skin barrier in atopic dermatitis mice models.

Chemical/toxin1 linked therapy

2018

PMID 32595401Rat

Examination of the Effects of Celecoxib on Postmastectomy Seroma and Wound Healing.

Wound1 linked therapy

2017

PMID 26886836Mixed

Omega-3 Fatty Acid Protects Against Arsenic Trioxide-Induced Cardiotoxicity In Vitro and In Vivo.

Chemical/toxin1 linked therapy

2017

PMID 27406816Rat

Simvastatin Therapy in the Acute Stage of Traumatic Brain Injury Attenuates Brain Trauma-Induced Depression-Like Behavior in Rats by Reducing Neuroinflammation in the Hippocampus.

TBI1 linked therapy

2017

PMID 27646597Rat

Protection Provided by a Gabexate Mesylate Thermo-SensitiveGel for Rats with Grade III Pancreatic Trauma.

Other1 linked therapy

2017

PMID 27648695Rat

Tranexamic Acid Attenuates The Loss of Lung Barrier Function in a Rat Model of Polytrauma And Hemorrhage With Resuscitation.

Haemorrhage/shock1 linked therapy

2017

PMID 27668315Mouse

Evaluation of Lecithinized Superoxide Dismutase for the Prevention of Acute Respiratory Distress Syndrome in Animal Models.

Endotoxin/LPS1 linked therapy

2017

PMID 27869558Mouse

Polynitroxylated Pegylated Hemoglobin-A Novel, Small Volume Therapeutic for Traumatic Brain Injury Resuscitation: Comparison to Whole Blood and Dose Response Evaluation.

TBI1 linked therapy

2017

PMID 27875498Mouse

A Murine Model of Robotic Training to Evaluate Skeletal Muscle Recovery after Injury.

Other1 linked therapy

2017

PMID 27881040Rat

A Single Dose of Docosahexaenoic Acid Increases the Functional Recovery Promoted by Rehabilitation after Cervical Spinal Cord Injury in the Rat.

Spinal cord injury1 linked therapy

2017

PMID 27882474Rat

Effects of CCK-8 and Cystathionine gamma-Lyase/Hydrogen Sulfide System on Acute Lung Injury in Rats.

Endotoxin/LPS1 linked therapy

2017

PMID 27889957Mouse

Acute or Delayed Treatment with Anatabine Improves Spatial Memory and Reduces Pathological Sequelae at Late Time-Points after Repetitive Mild Traumatic Brain Injury.

TBI1 linked therapy

2017

PMID 27901476Rat

The change of HCN1/HCN2 mRNA expression in peripheral nerve after chronic constriction injury induced neuropathy followed by pulsed electromagnetic field therapy.

Crush1 linked therapy

2017

PMID 27902477Mixed

Astragalus polysaccharide restores autophagic flux and improves cardiomyocyte function in doxorubicin-induced cardiotoxicity.

Chemical/toxin1 linked therapy

2017

PMID 27918369Mouse

Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.

Endotoxin/LPS1 linked therapy

2017

PMID 27926492Rat

The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord injury.

Spinal cord injury1 linked therapy

2017

PMID 27931151Rat

Regulation of Mitochondrial Function and Glutamatergic System Are the Target of Guanosine Effect in Traumatic Brain Injury.

TBI1 linked therapy

2017

PMID 27937036Mouse

Gastroprotective activity of the resin from Virola oleifera.

Chemical/toxin1 linked therapy

2017

PMID 27974687Mouse

The effects of pprI gene of Deinococcus radiodurans R1 on acute radiation injury of mice exposed to 60Co gamma-ray radiation.

Radiation1 linked therapy

2017

PMID 27983767Rat

Sulphoraphane Improves Neuronal Mitochondrial Function in Brain Tissue in Acute Carbon Monoxide Poisoning Rats.

Chemical/toxin1 linked therapy

2017

PMID 27987324Mixed

TUDCA: An Agonist of the Bile Acid Receptor GPBAR1/TGR5 With Anti-Inflammatory Effects in Microglial Cells.

Other1 linked therapy

2017

PMID 28008646Mouse

Acute cardiac support with intravenous milrinone promotes recovery from early brain injury in a murine model of severe subarachnoid haemorrhage.

Haemorrhage/shock1 linked therapy

2017

PMID 28030490Mouse

Modeling Acinetobacter baumannii wound infections: The critical role of iron.

Crush1 linked therapy

2017

PMID 28030501Rat

Apocynin suppressed the nuclear factor-kappaB pathway and attenuated lung injury in a rat hemorrhagic shock model.

Haemorrhage/shock1 linked therapy

2017

PMID 28062253Rat

Spinal neuropeptide expression and neuropathic behavior in the acute and chronic phases after spinal cord injury: Effects of progesterone administration.

Spinal cord injury1 linked therapy

2017

PMID 28068836Mouse

Electro-Acupuncture Modulates L1 Adhesion Molecule Expression After Mouse Spinal Cord Injury.

Spinal cord injury1 linked therapy

2017

PMID 28069497Rat

A modified collagen scaffold facilitates endogenous neurogenesis for acute spinal cord injury repair.

Spinal cord injury1 linked therapy

2017

PMID 28074914Rat

Hydroxysafflor yellow A attenuates the expression of inflammatory cytokines in acute soft tissue injury.

Crush1 linked therapy

2017

PMID 28077004Rat

Endoplasmic Reticulum Stress Modulation as a Target for Ameliorating Effects of Blast Induced Traumatic Brain Injury.

TBI1 linked therapy

2017

PMID 28083978Rat

Factors enhancing the migration and the homing of mesenchymal stem cells in experimentally induced cardiotoxicity in rats.

Chemical/toxin1 linked therapy

1,251–1,300 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.