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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

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PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2018

PMID 30193318Rat

Caspase-2 Mediates Site-Specific Retinal Ganglion Cell Death After Blunt Ocular Injury.

Other1 linked therapy

2018

PMID 30194744Rat

Comparison of the detrimental features of microglia and infiltrated macrophages in traumatic brain injury: A study using a hypnotic bromovalerylurea.

TBI1 linked therapy

2018

PMID 30199348Rat

Targeted Temperature Management: Peltier's Element-Based Focal Brain Cooling Protects Penumbra Neurons from Progressive Damage in Experimental Cerebral Ischemia.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30201709Mouse

Tissue plasminogen activator promotes white matter integrity and functional recovery in a murine model of traumatic brain injury.

TBI1 linked therapy

2018

PMID 30203370Mouse

Post-stroke DHA Treatment Protects Against Acute Ischemic Brain Injury by Skewing Macrophage Polarity Toward the M2 Phenotype.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30204031Rat

Research on the Effects of Levetiracetam in Spinal Cord Injury Model in Rats: An Experimental Study.

Spinal cord injury1 linked therapy

2018

PMID 30205524Mouse

A Synthetic Peptide AWRK6 Alleviates Lipopolysaccharide-Induced Liver Injury.

Endotoxin/LPS1 linked therapy

2018

PMID 30206282Mouse

Bacillus velezensis A2 fermentation exerts a protective effect on renal injury induced by Zearalenone in mice.

Chemical/toxin1 linked therapy

2018

PMID 30211851Rat

Effects of Exendin-4 on pancreatic islets function in treating hyperglycemia post severe scald injury in rats.

Burn1 linked therapy

2018

PMID 30211852Rat

Blood purification by nonselective hemoadsorption prevents death after traumatic brain injury and hemorrhagic shock in rats.

TBI1 linked therapy

2018

PMID 30212371Rat

Extract of Berula angustifolia (L.) Mertens Enhances Wound Healing in Streptozotocin-induced Diabetic Rats.

Wound1 linked therapy

2018

PMID 30216653Mouse

Mesenchymal stromal cell potency to treat acute kidney injury increased by ultrasound-activated interferon-gamma/interleukin-10 axis.

Chemical/toxin1 linked therapy

2018

PMID 30218079Rat

Integrative analysis of differentially expressed genes and miRNAs predicts complex T3-mediated protective circuits in a rat model of cardiac ischemia reperfusion.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30219993Rat

Uric Acid Treatment After Stroke Prevents Long-Term Middle Cerebral Artery Remodelling and Attenuates Brain Damage in Spontaneously Hypertensive Rats.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30221717Mixed

Protective effect of berberine on aconite-induced myocardial injury and the associated mechanisms.

Chemical/toxin1 linked therapy

2018

PMID 30221740Rat

Complement depletion with cobra venom factor alleviates acute hepatic injury induced by ischemia-reperfusion.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30224451Mouse

IL-33 promotes recovery from acute colitis by inducing miR-320 to stimulate epithelial restitution and repair.

Chemical/toxin1 linked therapy

2018

PMID 30229813Rat

Overexpression of miR-381-3p promotes the recovery of spinal cord injury.

Spinal cord injury1 linked therapy

2018

PMID 30232030Rat

Biodegradation of ECM hydrogel promotes endogenous brain tissue restoration in a rat model of stroke.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30232272Mouse

IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30232343Mouse

Effects of incorporation of granule-lyophilised platelet-rich fibrin into polyvinyl alcohol hydrogel on wound healing.

Wound1 linked therapy

2018

PMID 30236124Rat

Moderate hypothermia inhibits microglial activation after traumatic brain injury by modulating autophagy/apoptosis and the MyD88-dependent TLR4 signaling pathway.

TBI1 linked therapy

2018

PMID 30246455Rat

Inhibitory role of lentivirus-mediated aquaporin-4 gene silencing in the formation of glial scar in a rat model of traumatic brain injury.

TBI1 linked therapy

2018

PMID 30248482Mouse

NRF2 mitigates acute alcohol-induced hepatic and pancreatic injury in mice.

Chemical/toxin1 linked therapy

2018

PMID 30251917Rat

Multipotent Adult Progenitor Cells, but Not Tissue Inhibitor of Matrix Metalloproteinase-3, Increase Tissue Sparing and Reduce Urological Complications following Spinal Cord Injury.

Spinal cord injury1 linked therapy

2018

PMID 30255425Rat

Blood-Based Glutamate Scavengers Reverse Traumatic Brain Injury-Induced Synaptic Plasticity Disruption by Decreasing Glutamate Level in Hippocampus Interstitial Fluid, but Not Cerebral Spinal Fluid, In Vivo.

TBI1 linked therapy

2018

PMID 30258088Mouse

ERK activating peptide, AES16-2M promotes wound healing through accelerating migration of keratinocytes.

Wound1 linked therapy

2018

PMID 30260708Mouse

Stabilized collagen matrix dressing improves wound macrophage function and epithelialization.

Wound1 linked therapy

2018

PMID 30265898Mixed

Internal decompression of the acutely contused spinal cord: Differential effects of irrigation only versus biodegradable scaffold implantation.

Spinal cord injury1 linked therapy

2018

PMID 30276135Mixed

Nanotechnology in Wound Healing; Semisolid Dosage Forms Containing Curcumin-Ampicillin Solid Lipid Nanoparticles, in-vitro and in-vivo Characteristics.

Burn1 linked therapy

2018

PMID 30281685Rat

Effects of Rosuvastatin on Apolipoprotein J in Balloon-Injured Carotid Artery in Rats.

Other1 linked therapy

2018

PMID 30287503Rat

Zhenbao Pill reduces Treg cell proportion in acute spinal cord injury rats by regulating TUG1//HSP27 axis.

Spinal cord injury1 linked therapy

2018

PMID 30295956Mouse

Reactive oxygen species stimulated pulmonary epithelial cells mediate the alveolar recruitment of FasLkiller B cells in LPS-induced acute lung injuries.

Endotoxin/LPS1 linked therapy

2018

PMID 30304134Mouse

Cryotherapy: biochemical alterations involved in reduction of damage induced by exhaustive exercise.

Other1 linked therapy

2018

PMID 30312920Rat

Therapeutic effects of simultaneous Photobiomodulation therapy (PBMT) and Meloxicam administration on experimental acute spinal cord injury: Rat animal model.

Spinal cord injury1 linked therapy

2018

PMID 30327229Rat

Hypertonic saline resuscitation protects against kidney injury induced by severe burns in rats.

Burn1 linked therapy

2018

PMID 30327755Rat

Kynurenic Acid Protects against Thioacetamide-Induced Liver Injury in Rats.

Chemical/toxin1 linked therapy

2018

PMID 30333305Mouse

LNK deficiency promotes acute aortic dissection and rupture.

Other1 linked therapy

2018

PMID 30334381Mouse

Rescue from lethal acute radiation syndrome (ARS) with severe weight loss by secretome of intramuscularly injected human placental stromal cells.

Radiation1 linked therapy

2018

PMID 30334481Mouse

Leonurine ameliorates adriamycin-induced podocyte injury via suppression of oxidative stress.

Chemical/toxin1 linked therapy

2018

PMID 30336203Mouse

Preparation and protective effects of 1,8-cineole-loaded self-microemulsifying drug delivery system on lipopolysaccharide-induced endothelial injury in mice.

Endotoxin/LPS1 linked therapy

2018

PMID 30343257Rat

Neuroinflammation, oxidative stress, and blood-brain barrier (BBB) disruption in acute Utah electrode array implants and the effect of deferoxamine as an iron chelator on acute foreign body response.

TBI1 linked therapy

2018

PMID 30344125Mouse

Dysregulated bile acid signaling contributes to the neurological impairment in murine models of acute and chronic liver failure.

Chemical/toxin1 linked therapy

2018

PMID 30345583Rat

Nicotine impairs intra-substance tendon healing after full thickness injury in a rat model.

Other1 linked therapy

2018

PMID 30351197Mouse

Microglial Calcium Release-Activated Calcium Channel Inhibition Improves Outcome from Experimental Traumatic Brain Injury and Microglia-Induced Neuronal Death.

TBI1 linked therapy

2018

PMID 30358007Rat

Adalimumab mitigates ovarian ischemia-reperfusion injury in rats by regulating oxidative stress, apoptosis and resolution of inflammation.

Ischaemia-reperfusion1 linked therapy

2018

PMID 30358485Rat

Effects of Phenelzine Administration on Mitochondrial Function, Calcium Handling, and Cytoskeletal Degradation after Experimental Traumatic Brain Injury.

TBI1 linked therapy

2018

PMID 30360489Mouse

The Small Molecule NLRP3 Inflammasome Inhibitor MCC950 Does Not Alter Wound Healing in Obese Mice.

Wound1 linked therapy

2018

PMID 30362615Rat

Pharmacological induction of Heat Shock Protein 70 by celastrol protects motoneurons from excitotoxicity in rat spinal cord in vitro.

Spinal cord injury1 linked therapy

2018

PMID 30366525Mouse

Characteristic anti-inflammatory and antioxidative effects of enzymatic- and acidic- hydrolysed mycelium polysaccharides by Oudemansiella radicata on LPS-induced lung injury.

Endotoxin/LPS1 linked therapy

1,151–1,200 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.