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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2019

PMID 31580970Mouse

Inhibition of CACNA1H attenuates doxorubicin-induced acute cardiotoxicity by affecting endoplasmic reticulum stress.

Chemical/toxin1 linked therapy

2019

PMID 31581202Rat

Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury.

TBI1 linked therapy

2019

PMID 31581265Rat

Effect of tranexamic acid administration on acute traumatic coagulopathy in rats with polytrauma and hemorrhage.

Haemorrhage/shock1 linked therapy

2019

PMID 31582051Rat

A polysaccharide fraction from "ipe-roxo" (Handroanthus heptaphyllus) leaves with gastroprotective activity.

Chemical/toxin1 linked therapy

2019

PMID 31585800Mouse

MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury.

Endotoxin/LPS1 linked therapy

2019

PMID 31588948Rat

Pro-chondrogenic and immunomodulatory melatonin-loaded electrospun membranes for tendon-to-bone healing.

Other1 linked therapy

2019

PMID 31593807Mouse

A feasible biocompatible hydrogel film embedding Periplaneta americana extract for acute wound healing.

Wound1 linked therapy

2019

PMID 31599191Rat

Vitamin E protects against monosodium glutamate-induced acute liver injury and hepatocyte ultrastructural alterations in rats.

Chemical/toxin1 linked therapy

2019

PMID 31600096Rat

Sleep disordered breathing induced by cervical spinal cord injury and effect of adenosine A1 receptors modulation in rats.

Spinal cord injury1 linked therapy

2019

PMID 31600800Rat

Investigation of Bosentan's Effects on Pulmonary Contusion Created by Blunt Thoracic Trauma in Rats.

Crush1 linked therapy

2019

PMID 31601792Mixed

Inhibition of gap junction composed of Cx43 prevents against acute kidney injury following liver transplantation.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31601862Rat

Clinical-like cryotherapy improves footprint patterns and reduces synovial inflammation in a rat model of post-traumatic knee osteoarthritis.

Other1 linked therapy

2019

PMID 31601995Mouse

Hepatospecific ablation of p38alpha MAPK governs liver regeneration through modulation of inflammatory response to CCl4-induced acute injury.

Chemical/toxin1 linked therapy

2019

PMID 31603888Rat

Gingko Biloba protects cardiomyocytes against acute doxorubicin induced cardiotoxicity by suppressing oxidative stress.

Chemical/toxin1 linked therapy

2019

PMID 31604915Mouse

Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function.

Wound1 linked therapy

2019

PMID 31613219Mixed

Inhibition of ErbB kinase signalling promotes resolution of neutrophilic inflammation.

Endotoxin/LPS1 linked therapy

2019

PMID 31627170Mouse

1,4-Dithiothreitol treatment ameliorates hematopoietic and intestinal injury in irradiated mice: Potential application of a treatment for acute radiation syndrome.

Radiation1 linked therapy

2019

PMID 31630884Rat

Sodium Valproate Improves Skin Flap Survival via Gamma-Aminobutyric Acid and Histone Deacetylase Inhibitory System.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31634816Mouse

Anti-PcrV IgY antibodies protect against Pseudomonas aeruginosa infection in both acute pneumonia and burn wound models.

Burn1 linked therapy

2019

PMID 31641817Rat

Pharmacokinetics and anti-inflammatory effect of naproxen in rats with acute and subacute spinal cord injury.

Spinal cord injury1 linked therapy

2019

PMID 31642371Rat

Chronic, Twice-Daily Dosing of an NK2 Receptor Agonist [Lys,MeLeu,Nle]-NKA(4-10), Produces Consistent Drug-Induced Micturition and Defecation in Chronic Spinal Rats.

Spinal cord injury1 linked therapy

2019

PMID 31653830Mouse

Injectable human recombinant collagen matrices limit adverse remodeling and improve cardiac function after myocardial infarction.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31664513Rat

TRPM4-specific blocking antibody attenuates reperfusion injury in a rat model of stroke.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31665488Mouse

Protective effects of zingerone derivate on ionizing radiation-induced intestinal injury.

Radiation1 linked therapy

2019

PMID 31670896Rat

Possibilities and limitations of electrospun chitosan-coated polycaprolactone grafts for rotator cuff tear repair.

Other1 linked therapy

2019

PMID 31673056Mouse

Jagged1-mediated myeloid Notch1 signaling activates HSF1/Snail and controls NLRP3 inflammasome activation in liver inflammatory injury.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31675186Rat

Dual regulation of microglia and neurons by Astragaloside IV-mediated mTORC1 suppression promotes functional recovery after acute spinal cord injury.

Spinal cord injury1 linked therapy

2019

PMID 31676068Mouse

Critical role of IL-1beta in the pathogenesis of Agrocybe aegerita galectin-induced liver injury through recruiting T cell to liver.

Chemical/toxin1 linked therapy

2019

PMID 31678138Rat

Paradoxical effects of continuous high dose gabapentin treatment on autonomic dysreflexia after complete spinal cord injury.

Spinal cord injury1 linked therapy

2019

PMID 31678401Rat

Edaravone attenuates lung injury in a hind limb ischemia-reperfusion rat model: A histological, immunohistochemical and biochemical study.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31680116Rat

Protective Effects of MiR-129-5p on Acute Spinal Cord Injury Rats.

Spinal cord injury1 linked therapy

2019

PMID 31681309Mouse

A Frog-Derived Immunomodulatory Peptide Promotes Cutaneous Wound Healing by Regulating Cellular Response.

Wound1 linked therapy

2019

PMID 31687083Mouse

Mechanism of KLF4 Protection against Acute Liver Injury via Inhibition of Apelin Signaling.

Chemical/toxin1 linked therapy

2019

PMID 31690812Mouse

Short-term inhibition of fibrinolytic system restores locomotor function after spinal cord injury in mice.

Spinal cord injury1 linked therapy

2019

PMID 31693919Mouse

Pro-inflammatory cytokines serve as communicating molecules between the liver and brain for hepatic encephalopathy pathogenesis and Lycium barbarum polysaccharides protection.

Chemical/toxin1 linked therapy

2019

PMID 31711546Mouse

Peripheral loss of EphA4 ameliorates TBI-induced neuroinflammation and tissue damage.

TBI1 linked therapy

2019

PMID 31711898Rat

Decellularized brain matrix enhances macrophage polarization and functional improvements in rat spinal cord injury.

Spinal cord injury1 linked therapy

2019

PMID 31713675Rat

Lactobacillus helveticus R0052 alleviates liver injury by modulating gut microbiome and metabolome in D-galactosamine-treated rats.

Chemical/toxin1 linked therapy

2019

PMID 31718264Rat

Neuroprotective effects of P7C3 against spinal cord injury in rats.

Spinal cord injury1 linked therapy

2019

PMID 31724341Mouse

Dexamethasone fails to improve bleomycin-induced acute lung injury in mice.

Chemical/toxin1 linked therapy

2019

PMID 31726970Rat

Transcriptomic analysis of alpha-synuclein knockdown after T3 spinal cord injury in rats.

Spinal cord injury1 linked therapy

2019

PMID 31728280Mouse

Sexual Dimorphism of Gut Microbiota Dictates Therapeutics Efficacy of Radiation Injuries.

Radiation1 linked therapy

2019

PMID 31736768Mouse

Mineralocorticoid Receptor Signaling Contributes to Normal Muscle Repair After Acute Injury.

Chemical/toxin1 linked therapy

2019

PMID 31739103Rat

Phytochemical analysis and wound healing studies on ethnomedicinally important plant Malva neglecta Wallr.

Wound1 linked therapy

2019

PMID 31744501Mouse

Protective effect of Shenmai injection on doxorubicin-induced cardiotoxicity via regulation of inflammatory mediators.

Chemical/toxin1 linked therapy

2019

PMID 31745698Mixed

Role of the antioxidant properties in the gastroprotective and gastric healing activity promoted by Brazilian green propolis and the healing efficacy of Artepillin C.

Chemical/toxin1 linked therapy

2019

PMID 31747966Mouse

CD51 distinguishes a subpopulation of bone marrow mesenchymal stem cells with distinct migratory potential: a novel cell-based strategy to treat acute myocardial infarction in mice.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31759624Rat

Electrical stimulation of the vagus nerve improves intestinal blood flow after trauma and hemorrhagic shock.

Haemorrhage/shock1 linked therapy

2019

PMID 31775156Mouse

An acute immune response underlies the benefit of cardiac stem cell therapy.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31780865Mouse

Evidence That the Anti-Inflammatory Effect of Rubiadin-1-methyl Ether Has an Immunomodulatory Context.

Endotoxin/LPS1 linked therapy

751–800 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.