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RESEARCH WORKSPACE

Overview Therapies2,752 Studies Translation & outcomes Mechanisms Research gaps Safety findings

Methods & citation

August 2026 datasetResearch window · 1980–2020

A project by Pebble.

PEBBLE / ATLAS

Open research access

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Research linked to primary sources.Privacy CookiesDataset: 25 August 2026

THE UNDERLYING RESEARCH

Studies

Return to the publications. Inspect the model, extracted findings and therapies linked to each study.

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Filters Injury, species

Injury model

BurnChemical/toxinCrushEndotoxin/LPSFractureHaemorrhage/shockIschaemia-reperfusionOtherRadiationSpinal cord injuryTBIWound

Species

Guinea pigHamsterMixedMouseRabbitRat

Match any within a group; all selected groups must match.

4,095 matching study records4,081 PMIDs + 14 records without a PMID

2019

PMID 31397209Mouse

Depletion of Microglia Attenuates Dendritic Spine Loss and Neuronal Apoptosis in the Acute Stage of Moderate Traumatic Brain Injury in Mice.

TBI1 linked therapy

2019

PMID 31398924Rat

Intranasally Administered Exosomes from Umbilical Cord Stem Cells Have Preventive Neuroprotective Effects and Contribute to Functional Recovery after Perinatal Brain Injury.

TBI1 linked therapy

2019

PMID 31400930Mouse

Schisandra chinensis acidic polysaccharide partialy reverses acetaminophen-induced liver injury in mice.

Chemical/toxin1 linked therapy

2019

PMID 31409825Mouse

RORalpha suppresses interleukin-6-mediated hepatic acute phase response.

Chemical/toxin1 linked therapy

2019

PMID 31414732Rat

Effect of PI3K/PKB signal pathway inhibitor wortmannin pretreatment on intestinal barrier function in severe acute pancreatitic rats.

Chemical/toxin1 linked therapy

2019

PMID 31421130Rat

Neuroprotection by nicotinamide mononucleotide adenylyltransferase 1 with involvement of autophagy in an aged rat model of transient cerebral ischemia and reperfusion.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31425494Mouse

Propranolol attenuates cognitive, learning, and memory deficits in a murine model of traumatic brain injury.

TBI1 linked therapy

2019

PMID 31432172Rat

Ulinastatin ameliorates LPS-induced pulmonary inflammation and injury by blocking the MAPK/NF-kappaB signaling pathways in rats.

Endotoxin/LPS1 linked therapy

2019

PMID 31433044Rat

Evaluation of the effects of erythropoietin and interleukin-6 in rats submitted to acute spinal cord injury.

Spinal cord injury1 linked therapy

2019

PMID 31441804Rat

Can a Partially Injured Donor Nerve Restore Elbow Flexion in an Acute Brachial Plexus Injury in Rats?

Other1 linked therapy

2019

PMID 31442590Mouse

Inhibition of neuronal ferroptosis in the acute phase of intracerebral hemorrhage shows long-term cerebroprotective effects.

Haemorrhage/shock1 linked therapy

2019

PMID 31446815Mouse

Comparison of the TLR4/NFkappaB and NLRP3 signalling pathways in major organs of the mouse after intravenous injection of lipopolysaccharide.

Endotoxin/LPS1 linked therapy

2019

PMID 31449279Rat

Raffia hookeri Ethanolic Pulp Extract Ameliorated Neuronal Damage and Brain Oxidative Stress Following Mechanical-Induced Traumatic Brain Injury in Rats.

TBI1 linked therapy

2019

PMID 31451729Rat

Effect of Protease Inhibitors in Healing of the Vaginal Wall.

Wound1 linked therapy

2019

PMID 31454420Mouse

Prothymosin alpha and its mimetic hexapeptide improve delayed tissue plasminogen activator-induced brain damage following cerebral ischemia.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31462256Mouse

Platelet-rich plasma activates AKT signaling to promote wound healing in a mouse model of radiation-induced skin injury.

Radiation1 linked therapy

2019

PMID 31464098Mouse

Radiation mitigation of the intestinal acute radiation injury in mice by 1-[(4-nitrophenyl)sulfonyl]-4-phenylpiperazine.

Radiation1 linked therapy

2019

PMID 31470983Mouse

Noble gas neuroprotection: xenon and argon protect against hypoxic-ischaemic injury in rat hippocampus in vitro via distinct mechanisms.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31471671Rat

Beneficial effects of bardoxolone methyl, an Nrf2 activator, on crush-related acute kidney injury in rats.

Crush1 linked therapy

2019

PMID 31472112Rat

Galantamine improves functional recovery and reduces lesion size in a rat model of spinal cord injury.

Spinal cord injury1 linked therapy

2019

PMID 31478241Mouse

In-Vivo Efficacy of Recombinant Human Hyaluronidase (rHuPH20) Injection for Accelerated Healing of Murine Retrocalcaneal Bursitis and Tendinopathy.

Other1 linked therapy

2019

PMID 31479670Mouse

Sika deer antler protein against acetaminophen-induced nephrotoxicity by activating Nrf2 and inhibition FoxO1 via PI3K/Akt signaling.

Chemical/toxin1 linked therapy

2019

PMID 31481754Mouse

CCL5 deficiency promotes liver repair by improving inflammation resolution and liver regeneration through M2 macrophage polarization.

Chemical/toxin1 linked therapy

2019

PMID 31489890Mouse

P1G10, the Proteolytic Fraction from, Stimulates Tissue Repair after Acute Exposure to Ultraviolet B Radiation.

Radiation1 linked therapy

2019

PMID 31493867Mouse

Role of ferroptosis in the process of acute radiation-induced lung injury in mice.

Radiation1 linked therapy

2019

PMID 31495270Mouse

Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Improve Liver Regeneration After Ischemia Reperfusion Injury in Mice.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31499069Mouse

XQ-1H alleviates cerebral ischemia in mice through inhibition of apoptosis and promotion of neurogenesis in a Wnt/beta-catenin signaling dependent way.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31512714Rat

A ZnO-curcumin nanocomposite embedded hybrid collagen scaffold for effective scarless skin regeneration in acute burn injury.

Burn1 linked therapy

2019

PMID 31513844Rat

Pioglitazone improves working memory performance when administered in chronic TBI.

TBI1 linked therapy

2019

PMID 31515511Mouse

Histone methyltransferase G9a protects against acute liver injury through GSTP1.

Endotoxin/LPS1 linked therapy

2019

PMID 31520915Mouse

Helenalin from Centipeda minima ameliorates acute hepatic injury by protecting mitochondria function, activating Nrf2 pathway and inhibiting NF-kappaB activation.

Endotoxin/LPS1 linked therapy

2019

PMID 31530210Mouse

HO-1 mitigates acute kidney injury and subsequent kidney-lung cross-talk.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31530901Mouse

alpha-AR overactivation induces cardiac inflammation through NLRP3 inflammasome activation.

Chemical/toxin1 linked therapy

2019

PMID 31535210Rat

Hybrid material for open abdomen: saving the wound from intestinal fistula.

Wound1 linked therapy

2019

PMID 31545222Mouse

Embelin can protect mice from thioacetamide-induced acute liver injury.

Chemical/toxin1 linked therapy

2019

PMID 31545248Rat

Proteomic analysis of therapeutic effects of Qingyi pellet on rodent severe acute pancreatitis-associated lung injury.

Other1 linked therapy

2019

PMID 31545299Mouse

Recombinant annexin A6 promotes membrane repair and protects against muscle injury.

Other1 linked therapy

2019

PMID 31550910Mouse

CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice.

TBI1 linked therapy

2019

PMID 31553983Rat

Administration of a 20-Hydroxyeicosatetraenoic Acid Synthesis Inhibitor Improves Outcome in a Rat Model of Pediatric Traumatic Brain Injury.

TBI1 linked therapy

2019

PMID 31556847Mouse

Mitigating Effects of 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) on Hematopoietic Acute Radiation Syndrome after Total-Body Ionizing Irradiation in Mice.

Radiation1 linked therapy

2019

PMID 31560695Mouse

Protective mechanism of 1-methylhydantoin against lung injury induced by paraquat poisoning.

Chemical/toxin1 linked therapy

2019

PMID 31560696Rat

Therapeutic efficacy of neuregulin 1-expressing human adipose-derived mesenchymal stem cells for ischemic stroke.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31560862Mouse

A modified cholera toxin B subunit containing an ER retention motif enhances colon epithelial repair via an unfolded protein response.

Chemical/toxin1 linked therapy

2019

PMID 31560952Mouse

Inhibition of xanthine oxidoreductase protects against contrast-induced renal tubular injury by activating adenosine monophosphate-activated protein kinase.

Chemical/toxin1 linked therapy

2019

PMID 31562917Mouse

Neuroprotective effects of docosahexaenoic acid against sub-acute manganese intoxication induced dopaminergic and motor disorders in mice.

Chemical/toxin1 linked therapy

2019

PMID 31567653Rat

N-acetylcysteine and atorvastatin alleviates lung injury due to ischemia-reperfusion injury in rats.

Ischaemia-reperfusion1 linked therapy

2019

PMID 31568772Mouse

Topical Application of a Mast Cell Stabilizer Improves Impaired Diabetic Wound Healing.

Wound1 linked therapy

2019

PMID 31569016Rat

Anti-oxidant activity reinforced reduced graphene oxide/alginate microgels: Mesenchymal stem cell encapsulation and regeneration of infarcted hearts.

Other1 linked therapy

2019

PMID 31569604Mouse

Acute Kahweol Treatment Attenuates Traumatic Brain Injury Neuroinflammation and Functional Deficits.

TBI1 linked therapy

2019

PMID 31575959Mouse

Mitigation of radiation-induced gastro-intestinal injury by the polyphenolic acetate 7, 8-diacetoxy-4-methylthiocoumarin in mice.

Radiation1 linked therapy

701–750 of 4,095

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The full review includes 5,033 publications. This searchable index represents the itemised subset; the 1990–2010 window is partially indexed. Extraction details are retained per therapy association.