Influence of chronic hypertension on injured and uninjured arteries in spontaneously hypertensive rats.
RatOtherSpontaneously hypertensive rats (SHR) and normotensive Wistar rats
Model: Acute arterial endothelial injury by aortic balloon denudation and carotid air injury
Myointimal thickening after arterial injury was markedly enhanced in hypertensive rats and was reduced by antihypertensive treatment, while endothelial regeneration was similar across groups.
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