Brain prostaglandins E2 and F2 alpha following neonatal asphyxia in the guinea pig.
Guinea pigIschaemia-reperfusionCerebral (MCAO/stroke)Pretreatment before asphyxiation
Model: Asphyxiation in a nitrogen atmosphere for 3 minutes or 3 minutes 40 seconds, with or without resuscitation using 95 per cent oxygen and 5 per cent carbon dioxide
Asphyxia for 3 minutes 40 seconds raised brain prostaglandin E2 without changing prostaglandin F2 alpha, while asphyxia followed by resuscitation raised prostaglandin F2 alpha with prostaglandin E2 unchanged. Indomethacin pretreatment lowered both prostaglandins below non-asphyxiated control levels…
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.