Anti-inflammatory effect of diclofenac-sodium ointment (cream) in topical application.
MixedChemical/toxinInbred rats, strain not specifiedMaleTopicalCream formulations containing 0.5, 0.75, 1.0 and 1.5 per ce…
Model: Carrageenan and croton oil acute oedema, increased vascular permeability, ultraviolet erythema, granulation tissue proliferation, and adjuvant arthritis
The cream base was the most effective vehicle and the 1.0 per cent preparation inhibited vascular permeability, acute oedema, ultraviolet erythema and adjuvant arthritis swelling, with activity comparable to indomethacin gel and greater than bufexamac cream and mobilat ointment. Effect on granulati…
Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.