Oxygen radical dependent lung damage following thermal injury of rat skin.
RatBurnUnspecifiedSystemic
Model: Acute thermal injury to rat skin at 70 degrees C for 30 seconds, with remote acute lung injury
Thermal injury produced progressive consumptive depletion of complement, appearance of C5a-related chemotactic activity in serum within the first hour with associated neutropenia, and progressive lung permeability increases over 6 hours. Protection from lung injury was afforded by complement deplet…
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