Effect of triiodo-L-thyronine on axonal regeneration in the rat spinal cord after acute compression injury.
RatSpinal cord injuryCompressionFemalen = 56 rats total, 28 in the T3 treatment group5 micrograms/kg dailyAfter injury, daily for 4 weeks
Model: Acute spinal cord compression injury at T-7
T3 did not improve clinical recovery, inclined-plane performance or pyramidal tract axon counts compared with controls, and did not affect the roughly 50 per cent retrograde axonal loss seen between 4 and 12 weeks in both groups.
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