Correction of serum opsonic defects after burn and sepsis by opsonic fibronectin administration.
RatBurnUnspecifiedInbred rats, strain not specifiedAfter burn injury, once opsonic fibronectin depletion had occurred (depletion e…
Model: Thermal burn injury with superimposed moderate or severe sepsis (staphylococcal challenge)
Burn injury acutely depleted opsonic fibronectin from 341 (SE 30) to 98 (SE 7) mg/L. Repletion corrected levels when sepsis was moderate, but with severe sepsis levels only reached 121 (SE 18) mg/L. The in vitro serum opsonic deficit improved partially, from 2.2 to 6.7 per cent of injected dose per…
Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.