The effect of blood transfusion, dopamine, and gamma hydroxybutyrate on posttraumatic ischemia of the spinal cord.
RatSpinal cord injuryCompressionFemaleTransfusion intravenous; dopamine by infusionAfter injury
Model: Acute clip compression of the spinal cord at T-1 with a clip exerting 175 g pressure
Uninjured animals had mean arterial pressure 120.0 (SD 17.0) mmHg with grey and white matter flows of 74.2 (SD 22.3) and 18.7 (SD 6.7) ml/100 g/min, while injured untreated animals had 82.5 (SD 14.1) mmHg and flows of 13.3 (SD 12.1) and 3.9 (SD 3.9). Transfusion raised pressure to 127.5 (SD 13.7) m…
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