Lithium stimulates the recovery of granulopoiesis following acute radiation injury.
MouseRadiationAdministered after irradiation
Model: 200 rad whole-body irradiation producing haematopoietic injury
Lithium increased granulopoietic recovery with significant elevations in marrow and spleen derived CFU-GM compared with irradiated controls, and a significant elevation in white cell count consisting mainly of neutrophils. Erythroid stem cells (CFU-E, BFU-E) and iron-59 incorporation were slightly…
Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.