Supplemental vitamin A prevents the acute radiation-induced defect in wound healing.
RatRadiationSprague-DawleyMaleOral (dietary)150,000 IU vitamin A per kg diet supplemented on top of a c…Started at, 2 or 4 days before, or 1 to 2 hours to 4 days after irradiation and…
Model: Acute whole-body irradiation (175 to 850 rad) combined with dorsal skin incision and subcutaneous polyvinyl alcohol sponge implantation
Supplemental vitamin A prevented the impaired wound healing and lessened weight loss, leukopenia, thrombocytopenia, thymic involution, adrenal enlargement, reduction in splenic weight and gastric ulceration in rats irradiated at 750 to 850 rad and wounded. The benefit was seen whether supplementati…
Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.