Intraoperative antegrade lavage and anastomotic healing in acute colonic obstruction.
RatWoundn = 15 patients; number of rats not statedIntraoperative intraluminal irrigationAt the time of resection and anastomosis
Model: Acute distal colonic obstruction managed by primary resection and anastomosis, with a parallel experimental rat model of anastomotic healing after acute obstruction
In 15 patients treated by primary resection and anastomosis there were two leaks (14 per cent) and operating time was prolonged. In the rat study intraoperative irrigation improved early anastomotic colonic collagen content (p less than 0.02) and proximal and distal perianastomotic collagen content…
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