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PRECLINICAL PUBLICATION · 1985

Cutaneous thermal burn and oxidant-mediated acute lung injury: appearance in serum of lung-related LDH isoenzyme.

Rat / Burn

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 3939305 ↗1985Reported benefit

Cutaneous thermal burn and oxidant-mediated acute lung injury: appearance in serum of lung-related LDH isoenzyme.

RatBurnUnspecified

Model: Cutaneous thermal burn of rat skin with secondary oxidant-mediated acute lung injury

Serum LDH-4 appeared after thermal injury and correlated linearly with indices of lung damage. Interventions that protect from oxidant-mediated lung injury, namely catalase, hydroxyl radical scavengers, iron chelators or neutrophil depletion, produced significant reductions in serum LDH-4 following…

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.