THERAPY DOSSIER · th-7b46a9d35eb2

Catalase, with hydroxyl radical scavengers and iron chelators

Biologic

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Burn
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 3939305 ↗1985Reported benefit

Cutaneous thermal burn and oxidant-mediated acute lung injury: appearance in serum of lung-related LDH isoenzyme.

RatBurnUnspecified

Model: Cutaneous thermal burn of rat skin with secondary oxidant-mediated acute lung injury

Serum LDH-4 appeared after thermal injury and correlated linearly with indices of lung damage. Interventions that protect from oxidant-mediated lung injury, namely catalase, hydroxyl radical scavengers, iron chelators or neutrophil depletion, produced significant reductions in serum LDH-4 following…

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.

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