Effect of Pseudomonas contamination or antibiotic decontamination of the GI tract on acute radiation lethality after neutron or gamma irradiation.
RatRadiationmaleGastrointestinal decontaminationGiven prior to irradiation
Model: Whole-body irradiation with fission neutrons (3.5 Gy and above), cyclotron-produced neutrons (4.9 Gy and above) or 137Cs gamma rays (9.6 Gy and above)
Antibiotic decontamination before irradiation increased median survival time by 1 to 5 days within the transitional dose range where death results from combined intestinal and haematopoietic injury, while Pseudomonas contamination reduced median survival time by 1 to 5 days over the same range. Nei…
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