Evaluation of topical therapy with silver-kaolin (Argostop) in an experimental model of burn wound sepsis.
RatBurnScaldInbred strain (not further specified)MaleTopical aerosol spray to the burn woundApplied after burn; also applied before bacterial inoculation in one arm and af…
Model: 20 per cent total body surface area full-thickness dorsal scald burn, with surface inoculation of 2.5 x 10^8 Pseudomonas aeruginosa to model burn wound sepsis
Healing rates and wound colonisation did not differ between silver-kaolin treated and untreated wounds. After inoculation, mortality was 100% untreated, 71% with silver-kaolin, 9% with 1 per cent silver sulphadiazine, 6% when silver-kaolin was applied before inoculation, and 50% with kaolin alone,…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.