Decompression of the spinal cord improves recovery after acute experimental spinal cord compression injury.
RatSpinal cord injuryCompressionInbred strain (not further specified)Femalen = 5 rats per cell in a factorial designSurgicalCompression forces 2.3, 16.9 and 53.0 gDecompression after 15, 60, 120 or 240 minutes of compression
Model: Clip compression injury of the spinal cord at C7-T1 at forces of 2.3, 16.9 or 53.0 g
Injury force was the major determinant of recovery: rats injured with the 2.3 g clip performed better than those injured at higher forces at all decompression times (p less than 0.0001), and the 16.9 g group outperformed the 53.0 g group at 15 minutes only (p less than 0.05). Time to decompression…
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