Mitigation of Hydrochloric Acid (HCl)-Induced Lung Injury in Mice by Aerosol Therapy of Surface-Active Nanovesicles Containing Antioxidant and Anti-inflammatory Drugs.
MouseChemical/toxinNebulised aerosol, pulmonary200 mg/kg body weight
Model: Hydrochloric acid induced acute lung injury in mice
Nebulised Dual-NV reduced pulmonary haemorrhage and protein leakage, restored airway patency to about 96 per cent, and lowered inflammatory cytokines and oxidative stress by about 95 per cent in acid injured mice.
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.