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PRECLINICAL PUBLICATION · 2020

Acute Wound Healing Potential of Marine Worm,Grube, 1878 Aqueous Extract on Sprague Dawley Rats.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 33488747 ↗2020Reported benefit

Acute Wound Healing Potential of Marine Worm,Grube, 1878 Aqueous Extract on Sprague Dawley Rats.

RatWoundSprague DawleyFemalen = 35 rats in total, 5 per group across seven groups, each rat…TopicalOintment at 0.1%, 0.5% and 1.0% weight per weight; about 30…Treatment started on the day of wounding (day 0)

Model: Paired full-thickness circular excisional skin wounds about 8 mm in diameter created on the dorsum with a disposable biopsy punch

The 1.0% ointment gave the fastest closure, reaching 88.1 plus or minus 1.3% healing at day 7 and 99.8 plus or minus 0.1% at day 14 versus 88.4 plus or minus 0.4% for untreated wounds, significantly faster than acriflavine at days 7 and 11 and comparable to 15% gamat oil, with denser collagen and m…

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.