Efficacy of Compound Herbal Medicine Tong-Xie-Yao-Fang for Acute Radiation Enteritis and Its Potential Mechanisms: Evidence from Transcriptome Analysis.
RatRadiationSprague-DawleyMalen = 48 rats in total, four groups of n = 12; three jejunal samp…Oral gavage4.92 g per 100 g body weight, given as 2 mL per 100 g per d…Started on day 1 after irradiation
Model: Acute radiation enteritis induced by a single whole-abdominal irradiation of 10 Gy using a linear accelerator
Tong-Xie-Yao-Fang significantly increased jejunal villus height and full thickness versus the irradiated control and improved mental state and food intake, with crypt depth and mucosal thickness unchanged, and an effect comparable with glutamine.
Extraction: extract · Supplied extraction confidence: 0.93. Machine-extracted fields require source verification.