Neuroprotective Effects of Milrinone on Experimental Acute Spinal Cord Injury: Rat Model.
RatSpinal cord injuryContusionWistar albinon = 36 rats in total, n = 9 per group across four groupsIntraperitonealImmediately after spinal cord injury
Model: Thoracic spinal cord contusion produced by weight-drop technique after laminectomy
Milrinone significantly improved neurological examination scores compared with untreated and saline-treated injury groups, reduced glutathione peroxidase, total oxidant status, 8-hydroxyguanosine and IL-6, raised IL-10 and total antioxidant status, and significantly lowered the histopathological sp…
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