Comparative Analysis of the Effectiveness of Some Biological Injected Wound Healing Stimulators and Criteria for Its Evaluation.
RatWoundWistarMalen = 112 wounds, four groups of 28 wounds, seven wounds per grou…Local injection into the wound edges0.2 mL per wound in all groups (0.1 mL lateral edge and 0.1…On the day of wounding
Model: Standardised square full-thickness acute skin wound on the back created with a patented device, depth to the latissimus dorsi fascia, mean area 123 mm2
Mesenchymal stem cells gave a rapid but short-lived benefit, being the only treatment to reduce wound area significantly by day 3, while collagen gave a delayed but sustained benefit with the smallest wound areas and highest complete epithelialisation at days 7 and 14. Deproteinised calf blood haem…
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