Construction of Microunits by Adipose-Derived Mesenchymal Stem Cells Laden with Porous Microcryogels for Repairing an Acute Achilles Tendon Rupture in a Rat Model.
RatOtherSprague-DawleyMalen = 64 rats randomised into four groups (16 per group), assesse…Local injection into the tendon defect gap120 adipose-derived stem cell-laden gelatin microcryogels s…At the time of tendon transection surgery
Model: Acute Achilles tendon rupture created by transection of the right Achilles tendon, leaving a gap defect
Both the cell-laden microcryogel group and the cells-alone group stimulated Achilles tendon healing, with the cell-laden microcryogel group giving the best macroscopic appearance, histological morphology, Achilles functional index and biomechanical properties without adverse immune reaction. Gelati…
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