Resveratrol ameliorates hepatic injury and modulates hepatic biomarkers of regeneration, apoptosis and survival in a rat model of blunt hepatic trauma.
RatCrushOther / unspecifiedWistar Albinon = 21 rats in total, n = 7 per group across three groupsIntraperitoneal injection10 mg/kgAfter induction of blunt hepatic trauma
Model: Blunt hepatic trauma
Resveratrol lowered serum AST, ALT and LDH relative to untreated trauma and reduced inflammation scores (1.42 plus or minus 0.53 versus 2.42 plus or minus 0.53, p = 0.001), with the highest Ki-67, Bcl-2 and Bax scores in the treated group.
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