Anti-biofilm and wound-healing activity of chitosan-immobilized Ficin.
RatWoundtopical application
Model: Staphylococcus aureus-infected skin wound in rats
Infected wound area halved after 4 days with Ficin compared with 6 days in control, and topical immobilised enzyme gave a 3-log reduction in Staphylococcus aureus counts by 6 days versus more than 10 days in control, with smoother reepithelialisation and more native-like collagen structure.
Extraction: extract · Supplied extraction confidence: 0.55. Machine-extracted fields require source verification.