Large-Scale Fabrication of Robust Artificial Skins from a Biodegradable Sealant-Loaded Nanofiber Scaffold to Skin Tissue via Microfluidic Blow-Spinning.
MouseWoundTopical application of the scaffold to the injury site
Model: Acute tissue damage models including vascular bleeding, hepatic haemorrhage, large-area abdominal wall defect and cutaneous wound
Microfluidic blow-spinning produced a large-area nanofiber scaffold of fibrinogen-loaded polycaprolactone/silk fibroin core-shell fibres with a mean diameter of 65 nm. In vivo the sealant-loaded scaffold rapidly repaired acute tissue damage including vascular bleeding and hepatic haemorrhage, and p…
Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.