The effect of direct-current field on recovery from experimental spinal cord injury.
RatSpinal cord injuryCompressionInbred strain not specifiedn = 40 rats in total, four groups of 10Implanted device applying a direct-current field to the injured cord14 microA treatment stimulator versus 0 microA control stim…Implanted after acute spinal cord injury
Model: Clip compression injury of the spinal cord at C7-T1 at two severities (17 g and 53 g clip force)
In the milder 17 g injury there were no significant differences between treated and control rats. In the severe 53 g injury, direct-current stimulation improved inclined-plane scores, motor evoked potential amplitude and the number of labelled cells in the red nucleus, raphe nuclei and vestibular n…
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