Laser treatment of synovial inflammatory process in experimentally induced microcrystalline arthritis in Wistar rats.
RatOtherWistarMalen = 24 animals across three groupsTranscutaneous irradiation of the patellar region of the right kneeStarted 48 hours after arthritis induction
Model: Experimentally induced microcrystalline (crystal-induced) arthritis of the knee joint
Laser therapy reduced granulocyte and fibroblast numbers, blood vessel proliferation, apoptosis, collagen and hydroxyproline accumulation and TNF-alpha and MMP-13 levels relative to untreated arthritis, indicating reduced synovial inflammation and tissue injury; glycosaminoglycan content did not di…
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