THERAPY DOSSIER · th-534524bbd6f8

Indium gallium aluminium phosphide (InGaAlP) 670 nm laser photobiomodulation

Device · InGaAlP 670 nm laser photobiomodulation; light-based device therapy.

Evidence & regulatory context

Mechanism: InGaAlP 670 nm laser photobiomodulation; light-based device therapy.
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 32519204 ↗2020Reported benefit

Laser treatment of synovial inflammatory process in experimentally induced microcrystalline arthritis in Wistar rats.

RatOtherWistarMalen = 24 animals across three groupsTranscutaneous irradiation of the patellar region of the right kneeStarted 48 hours after arthritis induction

Model: Experimentally induced microcrystalline (crystal-induced) arthritis of the knee joint

Laser therapy reduced granulocyte and fibroblast numbers, blood vessel proliferation, apoptosis, collagen and hydroxyproline accumulation and TNF-alpha and MMP-13 levels relative to untreated arthritis, indicating reduced synovial inflammation and tissue injury; glycosaminoglycan content did not di…

Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.

Loading the evidence…