Neuroprotective effect of lithium in cold-induced traumatic brain injury in mice.
MouseTBICryogenicBALB/cMale2 mmol/kg for prophylactic and acute treatment; subacute fo…Prophylactic (before injury) and acute (after injury) regimens tested, with a 3…
Model: Cold-induced (cryogenic) traumatic brain injury
Both prophylactic and acute lithium reduced infarct volume and apoptosis, and high dose lithium was the most mobile group on tail suspension testing with significantly reduced infarct volume at subacute follow-up. However, hippocampal atrophy occurred in both lithium groups and was significant bila…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.