Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein.

Gut microbiota-derived indole 3-propionic acid protects against radiation toxicity via retaining acyl-CoA-binding protein.

Model: Total body ionising irradiation producing acute radiation syndrome with haematopoietic and gastrointestinal injury

Oral IPA attenuated radiation-induced haematopoietic and gastrointestinal injury, lowered systemic inflammation and preserved epithelial integrity without promoting tumour growth; effects attributed to PXR/ACBP signalling.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.