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PRECLINICAL PUBLICATION · 2020

Wet-adhesive, haemostatic and antimicrobial bilayered composite nanosheets for sealing and healing soft-tissue bleeding wounds.

Mouse / Haemorrhage/shock

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 32417650 ↗2020Reported benefit

Wet-adhesive, haemostatic and antimicrobial bilayered composite nanosheets for sealing and healing soft-tissue bleeding wounds.

MouseHaemorrhage/shockUncontrolledTopical application to the woundApplied at the time of wounding

Model: Dorsal skin and liver bleeding wound models

The approximately 77 nm thick bilayered nanosheet adhered to irregular wet tissue, shortened clotting time to 4 min, achieved a bactericidal rate near 100%, and sealed and healed bleeding skin and liver wounds within two weeks.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.