Evidence & regulatory context
- Mechanism
- Dopamine-modified gelatin/antimicrobial-peptide nanosheet with calcium, layered with PCL; biomaterial construct.
- Target
- Not recorded
- Injury models
- Haemorrhage/shock
- Reported indication
- Not recorded
- First approval
- Not recorded
- Development stage
- Not recorded
- ChEMBL record
- Not recorded
- ChEMBL max phase
- Not recorded
- Synonyms
- Not recorded
- Note
- Not recorded
Clinical trials 0
0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
No linked human trial in this dataset.
Preclinical evidence 1
1 studies reported at therapy level; 1 evidence entries itemised.
MouseHaemorrhage/shockUncontrolledTopical application to the woundApplied at the time of wounding
Model: Dorsal skin and liver bleeding wound models
The approximately 77 nm thick bilayered nanosheet adhered to irregular wet tissue, shortened clotting time to 4 min, achieved a bactericidal rate near 100%, and sealed and healed bleeding skin and liver wounds within two weeks.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.