A comparative assessment of lengthening followed by end-to-end repair and isograft repair of chronically injured peripheral nerves.
RatOtherLewis (Rats, Inbred Lew)SurgicalRepair performed after a long delay following transection (chronic injury)
Model: Chronic peripheral nerve injury: transection of the sciatic nerve with repair performed after a long delay
Structural and functional outcomes after nerve lengthening with end-to-end repair were comparable to isograft repair, with no significant differences in functional recovery or axon growth. Outcomes for chronic injuries were less favourable than for acute injuries in both groups.
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