The poly-ADP ribose polymerase-1/apoptosis-inducing factor pathway may help mediate the protective effect of electroacupuncture on early brain injury after subarachnoid hemorrhage.
RatHaemorrhage/shockUnspecifiedSprague-Dawley
Model: Subarachnoid haemorrhage model in rats, assessing early brain injury
Electroacupuncture reduced apoptosis, PARP-1/AIF pathway protein expression, blood-brain barrier permeability, cerebral oedema and microglial activation after subarachnoid haemorrhage. Neurological function improved significantly.
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