PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2020

The poly-ADP ribose polymerase-1/apoptosis-inducing factor pathway may help mediate the protective effect of electroacupuncture on early brain injury after subarachnoid hemorrhage.

Rat / Haemorrhage/shock

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 32301816 ↗2020Reported benefit

The poly-ADP ribose polymerase-1/apoptosis-inducing factor pathway may help mediate the protective effect of electroacupuncture on early brain injury after subarachnoid hemorrhage.

RatHaemorrhage/shockUnspecifiedSprague-Dawley

Model: Subarachnoid haemorrhage model in rats, assessing early brain injury

Electroacupuncture reduced apoptosis, PARP-1/AIF pathway protein expression, blood-brain barrier permeability, cerebral oedema and microglial activation after subarachnoid haemorrhage. Neurological function improved significantly.

Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.